静脉营养输液袋中DEHP的溶出量研究

Determination of DEHP dissolving out of parenteral nutrient containers for single use

目的:建立测定一次性使用静脉营养输液袋中增塑剂邻苯二甲酸二-(2-乙基己基)酯(DEHP)溶出量的方法。方法:采用气相色谱-质谱联用仪对一次性使用静脉营养输液袋DEHP溶出量进行定量分析,优化了色谱与质谱实验条件。结果:用该法测定出了一次性使用静脉营养输液袋DEHP溶出量小于3 mg.套-1。结论:本方法灵敏度高,重复性好,简便可行,可用于静脉营养输液袋的质量控制。

Objective：To establish a method for quantitative determination of DEHP dissolving out of parenteral nutrient containers for single use.Method：GC-MS was used to quantitaty DEHP dissolving out of parenteral nutrient containers.GC and MS test conditions were optimized.Results：The amount of DEHP dissolving out of every parenteral nutrient containers for single use is not more than 3 mg.Conclusion：The method is sensitive,simple and good stability,which can be used for the quality control of parenteral nutrient containers for single use.