密穗马先蒿中黄酮和降倍半萜成分

Flavonoids and nor-sesquiterpenes of Pedicularis densispica

目的:研究密穗马先蒿Pedicularis densispica全草的化学成分。方法:运用多种分离手段,根据理化及波谱(1D,2D-NMR,MS)数据确定化合物的结构。结果:分离并鉴定了10个化合物,分别为acacetin(1),apigenin-7-O-β-glucopyrano-side(2),kaempferol-3,7-O-α-dirhamnopyranoside(3),scutellarein-7-O-β-glucopyranoside(4),chrysoeriol-7-O-β-glucopyranoside(5),pedicutricone A(6),dearabinosyl pneumonanthoside(7),salidroside(8),darendoside B(9),maltol-β-D-glucopyranoside(10),化合物类型涉及黄酮、降倍半萜等。结论:以上化合物均为首次从该植物中分离得到,除6,8外,其余化合物均为首次从该属植物中分离得到。

Objective： To study the chemical constituents of the whole plants of Pedicularis densispica. Method： The chemical constituents were isolated by various chromatographic methods and their structures were determined by chemical evidences and spectral data. Result： Ten compounds were isolated and identified as acacetin （1）, apigenin-7-O-β-glucopyranoside （2）, kaempferol-3,7-O- α-dirhamnopyranoside （3）, scutellarein-7-O-β-glucopyranoside （ 4 ）, chrysoeriol-7-O-β-glucopyranoside （ 5 ）, pedicutricone A （ 6 ）, dearabinosyl pneumonanthoside （ 7 ） , salidroside （ 8 ） , darendoside B （ 9 ） , and maltol-β-D-glucopyranoside （ 10 ）. Conclusion： These compounds were isolated from the titled plant for the first time. Except compounds 6 and 8, the others were obtained for the first time from the genus Pedicularis.