滇南狸尾豆叶的化学成分研究

Studies on chemical constituents from leaves of Uraria lacei

目的:研究滇南狸尾豆叶的化学成分。方法:对滇南狸尾豆叶乙醇提取物的乙酸乙酯部分采用硅胶柱色谱、Sephadex LH-20柱色谱等方法分离纯化;根据波谱学数据和理化性质进行结构鉴定。结果:分离得到11个化合物,分别鉴定为:柚皮素-7-O-β-D-葡萄糖苷(1)(,2S)-5,7-dimethoxy-4'-hydroxyflavan(2),dalbergioidin(3),5,7-dihydroxy-2'-methoxy-3',4'-methylenedioxyisoflavanone(4),5,7,4'-三羟基黄酮(5),5,7-dihydroxy-2',4'-dimethoxyisoflavanone(6),5,7,2',4'-tetrahydroxy-isoflavone(7),大黄素(8),水杨酸(9),胡萝卜苷(10),正二十四烷(11)。结论:所有化合物均为首次从该植物中分离得到。

Objective： To study the chemical constituents from leaves of Uraria lacei. Method： Chemical constituents were isolated by silica gel column and Sephadex LH-20, and identified by physiochemical and spectral analyses and by comparison with the standard compounds. Result： Eleven compounds were isolated and identified as naringenin-7-O-β-D-glucopyranside （1）, （2S）-5, 7- dimethoxy-4＇-hydroxyflavan （2）, dalbergioidin （ 3 ）, 5, 7-dihydroxy-2＇-methoxy-3＇, 4＇-methylenedioxyisoflavanone （ 4 ）, apigenin （5）, 5, 7-dihydroxy-2＇, 4＇-dimethoxyisoflavanone （6）, 5, 7, 2＇, 4＇-tetrahydroxyisoflavone （7）, emodin （8）, saliylic acid （9）, daucosterol （10）, and tetracosane （11）. Conclusion： All compounds were isolated from this plant for the first time.