近5年中药不良反应文献的统计分析

Chinese medicine adverse reactions′ literature statistical analysis in recent five years

国家食品药品监督管理局自2001年11月发布第1期《药品不良反应信息通报》至今已共有32期,报道了中西药66个品种的不良反应,其中涉及中药品种12个,有效地提醒了全社会对药品不良反应的关注。为统计分析近年来中药不良反应的文献报道情况,共搜集到2005年至2009年的中国知网的中国期刊全文数据库的医药卫生目录下中药不良反应相关部分文献462篇,从中筛选出中成药不良反应报告文献共计79篇。对79篇文献进行逐篇阅读,只有8.9%左右的文献能够正确辨识中药与西药,证明中医药工作者在对中药不良反应的认识上还有待很大的提高。

Since the state food and drug administration（SFDA） issued the first edition of adverse drug reaction（ADR） informa- tion in November, 2001, it has 32 edition, reported the drug 66 species of adverse reactions, involving the variety of 12 traditional Chinese medicines, it was effectively reminds all social concern of adverse drug reaction. For statistical analysis in recent years reported adverse drug reaction of prepared Chinese medicine, collected 462 literatures from 2005-09 CNKI Chinese journal full-text database of medicine health directory. In all the collections, about 94 literatures are closely related to adverse drug reaction report of prepared Chinese medicine. But there are only 7 references could identify traditional Chinese medicine and western medicine correctly in 72 literatures with the value of statistical analysis. That means only 8. 9% of literatures can correctly identify western medicine and Chinese traditional medicine. So it proved that TCM workers＇ knowledge of ADR remains to be greatly improved.