平阳霉素局部注射治疗瘢痕体质者寻常疣的临床观察

Clinical Observation of Local Injection of Pingyangmycin in the Treatment of Common Wart in Scar Diathesis Patients

目的:观察平阳霉素局部注射治疗瘢痕体质者寻常疣的疗效。方法:选择我院2009年3月-2010年3月收治的66例瘢痕体质寻常疣患者,分为治疗组和观察组。治疗组38例,采用平阳霉素注射液+利多卡因注射液混合后局部注射;对照组28例,采用电灼治疗。2组均观察45d。观察2组患者的治愈率及有无瘢痕形成。结果:治疗45d后,治疗组156颗疣治愈147颗,治愈率为94.23%,所有治愈疣均未见瘢痕形成;对照组121颗疣治愈105颗,治愈率为86.78%,均出现瘢痕。2组均有少数患者出现红肿,经干预后痊愈,未见其他严重不良反应发生。结论:平阳霉素局部注射对瘢痕体质者寻常疣的治疗效果好,不易形成瘢痕。

OBJECTIVE： To observe the therapeutic efficacy of local injection of pinyangmycin in the treatment of common wart in scar diathesis patients. METHODS： 66 common wart patients with scar diathesis admitted in our hospital from Mar. 2009 to Mar. 2010 were selected as observation objects. For the 38 cases in treatment group, pinyangmycin were diluted and dissolved in lidocaine and then local injection was executed. For the 28 cases in control group, fulguration was executed. For the 2 groups, cure rate and whether cars appeared were observed during the 45-day treatment. RESULTS： For the treatment group, 147 out of 156 （94.23%） warts were cured and no cars appeared after 45-day treatment. However, for the control group, 105 out of 121 （86.78%） warts were cured and scars appeared. No severe ADR occurred in 2 groups, a few patients suffered from swelling, and then they were cured after treatment. CONCLUSION： In the treatment of common wart in scar diathesis patients, local injection of pinyangmycin has good clinical effect and no scar appears.