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代谢介质在癌性恶病质中的作用及其机制 被引量:1

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摘要 恶病质目前没有明确的定义,一般认为是一种进行性的消耗状态,多见于威胁生命疾病的晚期,如恶性肿瘤、艾滋病、慢性阻塞性肺疾病、慢性肾衰竭等。大约50%的恶性肿瘤患者会出现癌性恶病质(cancercachexia,CC),其中20%直接死于CC。CC降低生活质量并缩短生存期,给这类病人带来极大危害,其发病机制尚不清楚,但一般认为是多因素的。虽然CC常会出现厌食,但是却不能单独用厌食引起的能量摄入下降来解释,而且,CC甚至可以出现在没有厌食症状的患者中。
出处 《医学研究杂志》 2011年第9期12-15,共4页 Journal of Medical Research
基金 国家自然科学基金资助项目(81071816)
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