摘要
目的:测定近交系MIJ和HFJ大鼠的血液生理、生化指标,并以它们的原始亲体动物Wistar远交群大鼠为参考,进行比较分析,了解近交系MIJ和HFJ大鼠血液生理、生化指标的表型特征。方法:利用XT-1800i全自动血球记数仪和HITACHI 7060-020全自动生化仪对MIJ、HFJ和Wistar大鼠24项血液常规值和27项血液生化值进行测定。结果:HFJ大鼠与同性别Wistar大鼠、MIJ大鼠与同性别Wistar大鼠、HFJ大鼠与同性别MIJ大鼠之间均有许多血常规指标和生化指标存在差异。HFJ大鼠不同性别间、MIJ大鼠不同性别间部分指标存在差异。结论:MIJ和HFJ近交系大鼠血液的生理、生化有不同表型,各有其独特的生物学特征。
AIM： To identify the phenotypic characteristics of the blood physiological and biochemical parameters in inbred MIJ rats and inbred HFJ rats.METHODS： Twenty-four blood routine parameters and 27 blood biochemical parameters in inbred MIJ rats,inbred HFJ rats and outbred Wistar rats（the original brood stock animal） were measured by XT-1800i automatic blood-cell-counting instrument and HITACHI 7060-020 automatic biochemical analyzer.RESULTS： With some same sex,many blood routine parameters and blood biochemical parameters between HFJ rats and Wistar rats,MIJ rats and Wistar rats,HFJ rats and MIJ rats were different.A few differences were also observed between male and female MIJ rats and between male and female HFJ rats.CONCLUSION： The blood physiological and biochemical phenotypes are different between MIJ and HFJ inbred rats,each with some unique features.
出处
《中国病理生理杂志》
CAS
CSCD
北大核心
2011年第9期1820-1823,共4页
Chinese Journal of Pathophysiology
基金
河北省科技支撑计划重点资助项目(No.09276426D)
河北省科技攻关计划资助项目(No.07275503)
