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整合素LFA-1研究进展 被引量：2

Progress of Integrin LFA-1 Research
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摘要 整合素是白细胞表面受体的主要家族,主要介导细胞与细胞外基质间的黏附,调节白细胞的迁移、存活、增殖和血管生成等过程中发挥关键作用。LFA-1作为白细胞整合素的重要成员具有复杂结构和重要生物学功能,该文就其近年研究进展情况做一综述。 Integrins,which are the main families of surface receptors on leucocytes,mediate adhesion between cells and extracellular matrix.They exert a stringent control on cell migration,survival,proliferation and angiogenesis,and so on.LFA-1,as an important member of leukocytic integrins,possesses complex construction and significant biological fuction.The research of LFA-1 will be summaried in recent years.
作者 于长清 马金柱 崔玉东
机构地区 黑龙江八一农垦大学生命科技学院
出处 《安徽农学通报》 2011年第19期50-53,共4页 Anhui Agricultural Science Bulletin
基金 黑龙江省科技攻关重点项目(编号:20020101487)
关键词 整合素 LFA-1 Α亚单位 Β亚单位 Integrins LFA-1 α subunit： β subunit
分类号 Q512.8 [生物学—生物化学]
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参考文献31

  • 1Smith A, Stanley P, Jones K, et al. The role of the integrin LFA - 1 in T - lymphocyte migration [ J ] . Immunol Rev, 2007, 218 : 135 - 146.
  • 2Rachel Evans, Irene Patzak, Lena Svensson, et al. Integrins in im- munity[J]. J Cell Sci, 2009, 122(Pt 2) :215 -225.
  • 3Zhang Y, Hayenga HN, Sarantos MR, et al. Differential regulation of neutrophil CD18 integrin function by di - and tri -valent cations: manganese vs. gadolinium [ J ] . Ann Biomed Eng, 2008, 36 (4) : 647 - 660.
  • 4El azreq MA, Bourgoin SG. Cytohesin - 1 regulates human blood neutrophil adhesion to endothelial cells through β2 integrin activation [J] . MolImmunol, 2011,48(12 -13) :1408 -1416.
  • 5Larson RS, Corbi AL, Springer T. Primary structure of the leukocyte function - associated molecule - 1 alpha subunit: an integrin with an embedded domain defining a protein superfamily [ J ] . J Cell Biol, 1989, 108:703 - 712.
  • 6Lofius JC, Smith GW. Integrin - mediated cell adhesion : the extra- cellular face[ J] . J Biol Chem, 1994, 269:25235 - 25238.
  • 7Lee JO, Rieu P, Amaout MA. Crystal structure of the A domain from the alpha subunit of integrin CR3 ( CD11 b/CD18 ) [ J ] . Cell, 1995, 80(4) :631-638.
  • 8Yalamanchili P, Lu C, Oxvig C, et al. Folding and function of I do- main - deleted Mac - 1 and lymphocyte function - associated antigen -1[J] . J Biol Chem, 2000, 275(29):21877-21882.
  • 9Xiong YM, Zhang L. Structure - function of the putative I - domain within the integrin beta 2 subunit[ J] . J Biol Chem, 2001,276(22) : 19340 - 19349.
  • 10Juan J Calvete. Structures of Integrin Domains and Concerted Con- formational Changes in the Bidirectional Signaling Mechanism of αⅡbβ3[J] . Exp Biol Med, 2004, 229:732-744.

二级参考文献37

  • 1[1]Gerardi A S.Bovine leukocyte adhesion deficiency:a review of a modern disease and its implications[J].Res Vet Sci,1996,61:183～186.
  • 2[2]Tajima M,Irie M,Kirisawa R,et al.The detection of a mutation of CD18 gene in bovine leukocyte adhesion deficiency (BLAD)[J].J Vet Med Sci,1993,55:145～146.
  • 3[3]Kishimoto T K,Hollander N,Robert T M,et al.Heterogeneous mutations in the beta subunit common to the LFA-1,Mac-1 and p150,95 glycoproteins cause leukocyte adhesion deficiency[J].Cell,1987,50:193～202.
  • 4[4]Becker D J,Lowe J B.Leukocyte adhesion deficiency type Ⅱ[J].Biochem Biophys Acta,1999,1 455:193～204.
  • 5[5]Renshaw H W,Chatburn C,Bryan G B,et al.Canine granulocytopathy syndrome:neutrophil dysfunction in a dog with recurrent infections[J].J Am Vet Med Assoc,1975,166:443～447.
  • 6[6]Hagemoser W A.Roth J A,Lofstedt J,et al.Granulocytopathy in a Holstein heifer[J].J Am Vet Med Assoc,1983,183:1 093～1 094.
  • 7[7]Giger U,Boxer L A,Simpson P J,et al.Deficiency of leukocyte surface glycoproteins Mol,LFA-1 and Leu M5 in a dog with recurrent bacterial infections:an animal model[J].Blood,1990,69:1 622～1 630.
  • 8[8]Kehrli M E Jr,Schmalstieg F C,Anderson D C,et al.Molecular definition of the bovine granulocytopathy syndrome:identification of deficiency of the Mac-1(CD11b/CD18) glycoprotein[J].Am J Vet Res,1990,51:1 826～1 836.
  • 9[9]Nagahata H,Nochi H,Tamoto K,et al.Bovine leukocyte adhesion deficiency in Holstein cattle[J].Can J Vet Res,1993,57:225～261.
  • 10[10]Tammen I,Klippert H,Kuczka A,et al.An improved DNA test for bovine leukocyte adhesion deficiency[J].Res Vet Sci,1996,60:218～221.

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安徽农学通报
2011年 第19期

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