摘要
PET-CT已成为当今恶性肿瘤诊断、分期及疗效评价必不可少的工具,但是,MRI具有比CT更好的软组织分辨力,还可提供多种生理功能、多序列和多参数成像,且无放射性损伤,其与PET提供的分子信息互补、融合,有望成为新的双模式显像工具,在基础和临床研究中将起着至关重要的作用。然而PET与MRI结合在技术上具有很多挑战,近几年来成为分子影像学研究的热点,并已取得了重大进展。该文对PET-MRI融合技术及设备、初步应用及多模式探针的研究进展等作相关综述。
PET-CT muhimodality imaging has become an essential tool for diagnosis, staging and therapeutic evaluation for malignancy. But MRI has better soft tissue resolution than CT, and provides a variety of functional imaging, multi-sequence and muhi-parameter imaging, and has no radiation damage. The integration of plentiful information from MRI and molecular information provided by PET is expected to become a new dual-mode imaging tool which will play a very important role in basic and clinical research. However, many challenges are existed in the combined PET and MRI technology, and it has become a focus in molecu- lar imaging research in recent years, and has made significant progress. This paper overviews the progresses of PET-MRI integration technologies and devices, preliminary applications and multimodality probes.
出处
《国际放射医学核医学杂志》
2011年第4期207-212,共6页
International Journal of Radiation Medicine and Nuclear Medicine
基金
国家自然科学基金(81071200
30830041)
关键词
正电子发射断层显像术
磁共振成像
分子影像技术
Positron-emission tomography
Magnetic resonance imaging
Molecular imaging techniques