摘要
嗅神经母细胞瘤（ENB）为临床少见的来源于鼻腔顶部的恶性肿瘤。目前，全世界范围内文献报道的ENB仅有1000余例。该肿瘤具有独特的临床、影像、组织学、免疫组化及分子特征。但目前仍没有标准的治疗方案。颅面联合手术仍为ENB的主要治疗手段，但因其技术复杂、操作难度大，故总体治疗效果仍不满意。该文结合近年来的相关文献报道，对ENB的临床、病理特点以及最新的治疗手段进行综述。
Esthesioneuroblastoma （ENB） is an uncommon malignant tumor of the nasal vault. With only about 1000 cases reported in the world. These tumors have distinctive clinical, radiographic, histologic, immunohistochemical and molecular features. The best treatment has yet to be defined. Bicranial-facial surgical approach remains the primary treatment for ENB. But for its technical complexity, the treatment effect is still not satisfied. This manuscript will review the clinical and pathologic feature, current treatment of ENB focusing on the recent advances in these tumors.
出处
《国际放射医学核医学杂志》
2011年第4期241-245,共5页
International Journal of Radiation Medicine and Nuclear Medicine
关键词
成感觉神经细胞瘤
嗅觉
放射疗法
药物疗法
外科手术
Esthesioneuroblastoma, olfactory
Radiotherapy
Drug therapy
Surgical procedures, operative
