992例健康体检者血浆同型半胱氨酸水平的调查与分析

The investigation and analysis of plasma homocysteine levels in 992 cases of healthy medical examinees

目的了解乌海市健康人群同型半胱氨酸水平。方法对该地区992例健康体检者的血浆同型半胱氨酸（Hcy）水平及血脂水平进行检测。血脂试剂由浙江伊利康公司提供（三酰甘油、总胆固醇采用酶法,高密度脂蛋白胆固醇、低密度脂蛋白胆固醇采用直接法）;Hcy由美康公司提供（Hcy采用循环酶法）。结果通过检测发现健康人群高Hcy检出率较高,为28%,其中男性达34.7%,女性为20.3%,并且女性年龄越大,血浆Hcy水平越高。而男性的Hcy总体水平高于女性;其中男性在30~50岁较其他年龄段高,而女性在60岁以上较其他年龄段高。总胆固醇、低密度脂蛋白胆固醇是随着年龄增高而增高。三酰甘油、高密度脂蛋白胆固醇年龄段不同,增高也不同。结论健康人群血浆Hcy水平存在年龄、性别差异,高Hcy血症的检出率较高。

Objective To find out the homocysteine levels of local healthy people.Methods The plasma homocysteine and lipid levels of 992 cases of local healthy people were tested.Results The positive rate（28%） was found to be higher in the healthy people than that of the unhealthy′s,in which the positive rate of males was 34.7% and females was 20.3%.Moreover the older a female was,the higher the positive rate could be.The overall Hcy level of males was higher than that of the females.The positive rate of males with the age between 30 and 50 was higher than that of other ages,while the positive rate of females with the age over 60 was higher than that of other ages.CHO,LDL-C increased as age increased.The TG and HDL-C levels varied in different ages.Conclusion The serum Hcy level varies in different age and gender.The people with higher Hcy level stand a higher chance to discover blood diseases.