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高渗氯化钠羟乙基淀粉40注射液对全髋置换术患者失血耐受性的影响 被引量:3

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摘要 目的探讨硬膜外复合全麻下,高渗氯化钠羟乙基淀粉40注射液(HH40)对全髋关节置换术患者失血耐受性的影响。方法 ASAⅠ或Ⅱ级全髋关节置换术患者40例,随机分为观察组和对照组。两组患者均施行硬膜外复合全麻,在麻醉平稳15 min后,观察组输注HH40 8 ml/kg,对照组输注乳酸钠林格氏液2,0 min内输完。记录术中出入量,监测平均动脉压(MAP)、心率(HR)、中心静脉压(CVP),测定红细胞压积(Hct)、血红蛋白(Hb)变化。结果两组出血量和输液量相比差异无统计学意义(P>0.05),但观察组输血量明显低于对照组(P<0.05);观察组Hct和Hb在术毕和术后1 d明显低于基础值及对照组(P均<0.05),但均在正常范围。结论硬膜外复合全身麻醉下全髋关节置换术患者静脉输注HH40安全好,可有效提高患者对失血的耐受性。
出处 《山东医药》 CAS 北大核心 2011年第33期63-64,共2页 Shandong Medical Journal
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