2006～2009年门诊处方抗菌药物应用情况分析

Analysis of Application of Antimicrobial Drugs in Outpatient Prescriptions from 2006 to 2009

目的根据医院门诊抗菌药物的应用情况,评价门诊抗菌药物使用的合理性。方法采用回顾性调查方法,按照卫生部抗菌药物临床应用监测网处方抽样方法,从华中科技大学同济医学院附属同济医院2006～2009年度的普通门诊处方中抽取固定数量的处方,统计出抗菌药物的不同种类的品种比、金额比、联用情况,给药途径,用药频度(DDDs)以及日用药金额(DDC)。结果 4 a来该院门诊处方以使用一种抗菌药物为主,使用一种抗菌药物的比例基本在85%以上。抗菌药物总金额占处方总金额的比例变化不大,但抗菌药物的处方金额呈上升趋势。抗菌药物的应用一直以β-内酰胺类和喹诺酮类为主,两者的品种数比例和金额比例之和均>60%。通用名的使用率逐年增加,从19%上升到52%。结论该院抗菌药物的使用基本合理。应继续加强对临床抗菌药物使用的监管,严格用通用名称开具处方,强化药品费用的控制。

Objective To evaluate the rationality of clinical use of antimicrobial drugs according to application of antibiotics in outpatient prescriptions. Methods With a retrospective survey and antibiotics clinical application monitory network of the Ministery of Health,fixed number of outpatient prescriptions was randomly selected from the year of 2006-2009,and the ratio of different drug categories,consumption amount,combined usage of drugs,administration routes,DDDs and daily drug costs（DDC） were calculated. Results During the four years,only one antimicrobial drug was used in most prescriptions,and the ratio was kept over 85%.There was little change in the total consumption amount of the antimicrobial drugs,but there existd the elevating trend of consumption amount of antibiotics prescriptions.The antibiotics of β-lactam and quinolone were widely used,the ratio of these two was over 60% by years.The utilization rate of the generic names had increased from 19% to 52%. Conclusion The use of antibacterial drugs in our hospital is generally rational.The antibiotics monitoring should be kept on.At the same time,the use of generic names should be still enhanced and the supervision of drug costs should be enfored.