老年糖尿病非酮症高渗性昏迷22例的临床及预后因素分析

Analysis of clinical data and prognosis-correlated factors of 22 senile patients with diabetic nonketotic hyperosmolar

目的探讨老年糖尿病非酮症高渗性昏迷(DNHC)的发病诱因,代谢指标和基础疾病与预后的关系。方法对我院内分泌科2006～2011年期间收治的22例老年DNHC患者临床资料进行回顾性分析。结果老年DNHC的主要诱因为感染,占45.4%。老年DNHC患者的预后与基础疾病积分、休克及急性肾功能衰竭呈显著负相关(P<0.05)。结论早期确诊和及时正确的治疗是降低老年DNHC病死率的关键。加强糖尿病教育,保持血糖长期良好控制是降低老年DNHC病死率的根本。

Objective To discuss the correlation between causative factors,metabolic indexes,primary diseases and the prognosis of diabetic nonketotic hyperosmolar coma（DNHC）in senile people.Methods A retrospective analysis of the clinical data was made among 22 senile patients with DNHC who were hospitalized in the Department of Endocrinology in our hospital from 2006 to 2011.Results Infection was the major cause for DNHC in these patients,which accounted for 45.4% of the 22 cases.The prognosis of the senile DNHC patients had a significant negative correlation with the primary disease,shock and acute renal failure（P0.05）.Conclusion Early diagnosis and correct treatment in time are the key points to reduce DNHC case fatality in senile patients.Good education of diabetes and long-term fine control of the blood glucose are fundamental to reduce the case fatality.