基于症候群监测初步建立我国口岸入境人员传染病监测网络及其2009—2011年监测结果分析

The initial establishment and analysis on the surveillance network platform of infectious diseases among entry personnel at ports based on syndrome monitoring during 2009 to 2011

目的了解我国入境人群发热症候群和腹泻症候群的病原谱构成数据,促进我国入境传染病网络实验室监测网络技术平台建立和完善。方法通过口岸体温监测、医学巡查、主动申报、健康体检等手段,于2009年5月—2011年3月间,联合9个直属检验检疫局所属口岸建立监测哨点并对筛选出的入境发热及腹泻人员进行样本采集、统一病原谱检测及数据分析方法。结果 9个哨点口岸共采集来自包括5大洲36个国家及地区的1878例样本,其中,阳性样本数为964例,检测出20种阳性病原体,总病原检出率为51.33%。发热伴呼吸道症候群、腹泻症候群和其他症候群阳性检出率进行比较,差异有统计学意义;采集样本中季节性甲型流感病毒、乙型流感病毒和2009甲型H1N1流感各年龄组阳性样本率进行比较,差异有统计学意义,三者的阳性样本25-年龄组最高,60岁以上人群的阳性样本数较低;9个哨点口岸阳性样本检出率进行比较,差异有统计学意义;中国籍和外籍入境人员样本流感病毒与其他病毒检出率进行比较,差异有统计学意义。结论通过统一的传染病样本监测方法,初步建立我国入境口岸传染病监测网络技术平台。

Objective To obtain the data of pathogen spectrum constitute of the entry infectious diseases and to establish the surveillance network technology platform of the entry Infectious diseases initially in China. Methods The surveillance on infectious diseases among fever and diarrhea-like cases at entry ports in 2009.5 - 2011.3 were carried out through temperature screening, health declaration, medical patrol and health examination and the pathogen spectrum were analyzed on the corresponding samples. Results 1878 samples were collected totally which originated from the five continents, 36 countries and regions, A total of 20 positive pathogens and 964 samples were found positively and the positive rate was 51.33%. The difference of the positive detection rate of the febrile respiratory syndrome, diarrhea syndrome and the other syndrome was statistically significant; there were significant difference among seasonal influenza A virus, influenza B virus and 2009 Influenza A （H1N1） of the positive detection rate in all age groups; these positive samples were tile highest in 25 year old group and the lowest beyond 60 year old groups; the difference of positive detection rate among the nine points of entry was statistically significant; the difference the detection of influenza A virus and other kinds of viruses of the chinese and foreign entry staffs was statistically significant. Conclusion The network technology platform of the surveillance on infectious diseases in china points of entry have been established initially.