GC法测定喉疾灵片中冰片含量的方法研究

Determination of Borneol in Houjiling Tablets by GC

目的建立GC法测定喉疾灵片中冰片的含量测定方法。方法采用Rtx-50毛细管柱(30 m×0.25 mm,0.25μm),载气为氮气,FID检测器,柱温为恒温130℃,内标法测定冰片含量。结果冰片在0.405 4～2.027 0 g.L-1范围内浓度与峰面积呈良好的线性关系(r=0.999 0,n=5),平均加样回收率为99.21%,RSD为0.81%(n=9)。结论该方法快速、灵敏、结果准确,适用于喉疾灵片中冰片的含量测定。

Aim To establish a GC method for the determination of Borneol in Houjiling tablets.Methods The Rtx-50 capillary column（30 m×0.25 mm,0.25 μm） was used with FID,nitrogen as the carrier gas,column temperature at 130 ℃.The internal standard method was used to determine the content of borneol.Results The borneol sample showed a good linear relationship at the range of 0.405 4~2.027 0 g·L-1（r=0.999 0,n=5）.The average recovery rate was 99.21% and RSD was 0.81%（n=9）.Conclusion This method is simple and accurate and able to determine of Borneol in Houjiling Tablets.