硬膜外阻滞联合异氟醚吸入对胃癌手术患者血流动力学影响研究

Epidural Block Combined with Isoflurane on Hemodynamics in Patients with Gastric Cancer

目的:观察硬膜外阻滞联合异氟醚吸入对胃癌手术患者血流动力学的影响。方法:将71例患者随机分为两组,36例患者采取硬膜外阻滞联合异氟醚吸入为观察组,35例患者采取异氟醚吸入全麻为对照组。观察并记录两组患者术前(T0)、诱导后即刻(T1)、切皮时(T2)、切皮后100 min(T3)、关腹时(T4)、拔管后10min(T5)NIBP和HR。结果:两组患者在手术过程中均未出现低血压现象,且HR维持良好,对照组患者在切皮时(T2)、切皮后100 min(T3)、关腹时(T4),SBP、DBP均下降明显,但很快又回升,未造成严重后果,观察组患者相比对照组患者而言,三项指标均倾向于更稳定,仅在诱导后即刻SBP和DBP有所下降。结论:对胃癌手术患者采取硬膜外阻滞联合异氟醚吸入全麻,患者血流动力学稳定,无低血压现象发生。

Objective：To observe the influencecf the epidural block combined with isoflurane on hemo-dynamics in patients with gastric cancer.Method：We observed and recorded the NIBP and HR of the pa-tients in two groups before surgery（T0）,immediately after induction（T1）,skin incision（T2）,100 min af-ter incision（T3）,the abdomen was closed（T4）,10min after extubation（T5）.Result：The patients intwo groups were without the phenomenon of hypotension during surgery,patients in control group in the skinincision（T2）,100 min after incision（T3）,the abdomen was closed（T4）,SBP and DBP decreased signifi-cantly,but soon rose again,no serious consequences in patients observed of group.Compared to the controlgroup,the three indicators tended to be more stable,only immediately after the induction of SBP and DBP declined.Conclusion：The hemodynamic is stable,no hypotension occurred in the patients with gastriccancer with epidural block combined with isoflurane anesthesia.