期刊文献+

维生素D缺乏与补充研究现状 被引量:27

Current research status of vitamin D deficiency and supplementation
下载PDF
导出
摘要 维生素D是维持骨骼健康必不可少的物质之一。目前全球约有10亿人维生素D不足或缺乏,大部分人需要额外补充维生素D来达到推荐的摄入量,而国外常用的补充剂是维生素D3(胆钙化醇)。现对老年人维生素D3的日推荐剂量一般在800IU以上,安全上限为2000IU。维生素D补充也是治疗骨质疏松症的基础。 Vitamin D is one of the most important hormones to maintain bone health.It has been estimated that 1 billion people worldwide have vitamin D deficiency or insufficiency.Most people require extra supplements of vitamin D to meet the recommended intake and vitamin D3 (cholecalciferol) is usually recommended abroad.Now most clinical trials recommended an intake of more than 800 international units (IU) of vitamin D per day for old adults,and the safe upper limit for vitamin D intake was set at 2 000 IU per day.Vitamin D is the fundamental treatment of osteoporosis now.
出处 《上海医药》 CAS 2011年第10期474-476,共3页 Shanghai Medical & Pharmaceutical Journal
关键词 维生素D 骨骼健康 骨质疏松症 vitamin D bone health osteoporosis
  • 相关文献

参考文献20

  • 1Holick MF.Vitamin D deficiency[J].N Engl J Med,2007,357(3):266-281.
  • 2Morales O,Samuelsson MK,Lindgren U,et al.Effects of 1alpha,25-dihydroxyvitamin D3 and growth hormone on apoptosis and proliferation in UMR 106 osteoblast-like cells[J].Endocrinology,2004,145(1):87-94.
  • 3Thomas MK,Lloyd-Jones DM,Thadhani RI,et al.Hypovitaminosis D in medical inpatients[J].N Engl J Med,1998,338(12):777-783.
  • 4Dawson-Hughes B,Heaney RP,Holick MF,et al.Estimates of optimal vitamin D status[J].Osteoporos Int,2005,16(7):713-716.
  • 5Lips P,Hosking D,Lippuner K,et al.The prevalence of vitamin D inadequacy amongst women with osteoporosis:An international epidemiological investigation[J].J Intern Med,2006,260(3):245-254.
  • 6Woo J,Lam CW,Leung J,et al.Very high rates of vitamin D insufficiency in women of child-bearing age living in Beijing and Hong Kong[J].Br J Nutr,2008,99(6):1330-1334.
  • 7朱汉民,程群,甘洁民,杜艳萍,洪维,朱晓颖,李慧林.上海地区人群维生素D状态研究[J].中华骨质疏松和骨矿盐疾病杂志,2010,3(3):157-163. 被引量:134
  • 8张浩,黄琪仁,章振林,顾洁梅,胡伟伟,刘玉娟,胡云秋,李淼.上海市绝经后妇女冬季维生素D状况[J].中国骨质疏松杂志,2011,17(1):43-46. 被引量:28
  • 9Vieth R.Why the optimal requirement for Vitamin D3 is probably much higher than what is officially recommended for adults[J].J Steroid Biochem Mol Biol,2004,89-90(1-5):575-579.
  • 10Dawson-Hughes B,Harris SS,Krall EA,et al.Effect of calcium and vitamin D supplementation on bone density in men and women 65 years of age or older[J].N Engl J Med,1997,337(10):670-676.

二级参考文献60

  • 1Lips P,Hosking D,Lippuner K,et al.The prevalence of vitamin D inadequacy amongst women with osteoporosis:an international epidemiological investigation.J Intern Med,2006,260(3):245-254.
  • 2Woo J,Lam CW,Leung J,et al.Very high rates of vitamin D insufficiency in women of child-bearing age living in Beijing and Hong Kong.Br J Nutr,2008,99(6):1330-1334.
  • 3Holick MF.Sunlight and vitamin D for bone health and prevention of autoimmune diseases,cancers and cardiovascular disease.Am J Clin Nutr,2004,80(6 Suppl):1678S-1688S.
  • 4Holick MF.Environmental factors that influence the cutaneous production of vitamin D.Am J Clin Nutr,1995,61 (3 Suppl):638S-645S.
  • 5van der Wielen RP,Lowik MR,van den Berg H,et al.Serum vitamin D concentrations among elderly people in Europe.Lancet,1995,346(8969):207-210.
  • 6Foo LH,Zhang Q,Zhu K,et al.Relationship between vitamin D status,body composition and physical exercise of adolescent girls in Beijing.Osteoporos Int,2009,20(3):417-425.
  • 7Nakamura K,Nashimoto M,Matsuyama S,et al.Low serum concentrations of 25-hydroxyvitamin D in young adult Japanese women; a cross sectional study.Nutrition,2001,17(11-12):921-925.
  • 8Holick MF,Matsuoka LY,Wortsman J.Age,vitamin D,and solar ultraviolet.Lancet,1989,2(8671):1104-1105.
  • 9Millen AE,Wactawski-Wende J,Pettinger M,et al.Predictors of serum 25-hydroxyvitamin D concentrations among postmenopausal women:the Women's Health Initiative Calcium plus Vitamin D clinical trial.Am J Clin Nutr,2010,91 (5):1324-1335.
  • 10Yan L,Zhou B,Wang X,et al.Older people in China and the United Kingdom differ in the relationships among parathyroid hormone,vitamin D,and bone mineral status.Bone,2003,33(4):620-627.

共引文献158

同被引文献226

引证文献27

二级引证文献263

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部