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大电导钙激活钾通道与妊娠的关系

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摘要 大电导钙激活钾通道（large conductanceCa2＋- activated K＋-channel，BKCa）由4个相同的α亚基构成的孔样通道及附属的β调节亚基（β1～β4）组成，因其电导大、对Ca2＋敏感、电压依赖性得名。BKCa广泛分布于哺乳动物除心肌外的各种组织细胞中，包括平滑肌、骨骼肌、神经元、肾脏和内分泌细胞等，并可通过多种调节因子直接作用于细胞核内DNA或作用于细胞膜上的相应受体而发挥多种生物学作用，在许多生理和病理过程中也发挥着重要作用。
作者 廖秋萍 颜建英
机构地区 福建医科大学教学医院福建省妇幼保健院妇产科
出处 《中华围产医学杂志》 CAS 2011年第10期633-637,共5页 Chinese Journal of Perinatal Medicine
关键词 大电导钙激活钾通道 妊娠 电压依赖性 内分泌细胞 生物学作用 调节亚基 Ca2+ 组织细胞
分类号 R714.1 [医药卫生—妇产科学]
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参考文献29

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二级参考文献26

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中华围产医学杂志
2011年 第10期

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