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老年心血管病患者的他汀治疗

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摘要 过去10年中,国内外先后完成了一系列里程碑式的降脂试验,这些研究结果有力论证了应用他汀降胆固醇治疗在冠心病及相关心血管疾病一、二级预防中的重要意义。
作者 郭艺芳 高丽君
机构地区 河北省人民医院老年病科
出处 《实用老年医学》 CAS 2011年第5期353-356,共4页 Practical Geriatrics
关键词 降胆固醇治疗 心血管病患者 他汀 老年 心血管疾病 降脂试验 二级预防 国内外
分类号 R972.6 [医药卫生—药品]
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参考文献10

  • 1Ford ES,Mokdad AH,Giles WH,et al.Serum total cholesterol concentrations and awareness,treatment,and control of hyprecholesterolemia among US adults:findings from the national health and nutrition examination survey,1999 to 2000[J].Circulation, 2003,107 (5):2185-2189.
  • 2Grundy SM.The role of cholesterol management in coronary disease risk reduction in elderly patients[J].Endocrinol Metab Clin North Am,1998,27(3):655-675.
  • 3Shepherd J,Cobbe SM,Ford I,et al.Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia[J].N Engl J Med,1995,333(20):1301-1307.
  • 4Downs JR,Clearfield M,Weis S,et al.Primary prevention of acute coronary events with lovastatin in men and women with average cholesterol levels:results of AFCAPS/TexCAPS.Air Force/Texas Coronary Atherosclerosis Prevention Study[J].JAMA,1998,279 (20):1615-1622.
  • 5Scandinavian Simvastatin Survival Study Group.Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease:the Scandinavian Simvastatin Survival Study (4S)[J].Lancet,1994,344(8934):1383-1389.
  • 6Sacks FM,Pfeffer MA,Moye LA,et al.The effect of pravastatin on coronary events after myocardial infarction in patients with average cholesterol levels.Cholesterol and Recurrent Events Trial investigators[J].N Engl J Med,1996,335 (14):1001-1009.
  • 7The Long-Term Intervention with Pravastatin in Ischaemic Disease (LIPID) Study Group.Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels[J].N Engl J Med,1998,339(19):1349-1357.
  • 8Heart Protection Study Collaborative Group.MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20,536 high-risk individuals:a randomised placebo-controlled trial[J].Lancet,2002,360 (9326):7-22.
  • 9Shepherd J,BlauwGJ,MurphyMB,et al.Pravastatin in elderly individuals at risk of vascular disease (PROSPER):a randomised controlled trial[J].Lancet,2002,360(9346):1623-1630.
  • 10杜保民,陆宗良,武阳丰,叶平,陈祚.中国冠心病二级预防研究——老年高血压人群的干预结果分析[J].中华老年心脑血管病杂志,2006,8(2):82-86. 被引量：17

二级参考文献7

  • 1血脂康调整血脂对冠心病二级预防研究协作组.中国冠心病二级预防研究[J].中华心血管病杂志,2005,33(2):109-115. 被引量：222
  • 2陆宗良,杜保民,武阳丰,陈祚.血脂康对老年人冠心病二级预防的作用[J].中华老年医学杂志,2005,24(11):805-808. 被引量：22
  • 3Scandinavian Simvastatin Survival Study Group. Randomised trial of cholesterol lowering on 4444 patients with coronary heart disease: the Scandinavian simvastatin survival study (4S) [J]. Lancet, 1994, 344:1383-1389.
  • 4Sacks FM, Pfeffer MA, Moye LA, et al. The effect of pravastatin on coronary events after myocardial infarction in patients with average cholesterol levels[J]. N Engl J Med, 1996,335 : 1001-1009,
  • 5The Lipid Study Group. Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels[ J ]. N Engl J Med, 1998,339:1349-1357.
  • 6Shepherd J, Blauw GJ, Murphy MB, et al. Pravastatin in elderly individuals at risk of vascular disease(PROSPER) : a randomized controlled trial[J] .The Lancet,2002,360:1623-1630.
  • 7Li ZP. Cholesterol-lowering effects and pharmacokinetics of Chinese red yeast rice[A]. In: Inaugural international congress on complementary and alternative medicine[ M ]. Singapore: Raffles City Convention Centre, 2005.94.

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实用老年医学
2011年 第5期

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