摘要
目的探讨环孢素A(cyclosporine A,CsA)联合氟康唑治疗真菌性角膜炎的临床效果。方法将127例真菌性角膜炎患者随机分为两组,A组为常规组采取氟康唑药物治疗,B组为治疗组在A组氟康唑治疗基础上加用CsA治疗。结果 B组在视力恢复、显效率及总有效率上明显优于A组,无效率也明显低于A组,差异有统计学意义。结论 CsA联合氟康唑能明显提高真菌性角膜炎的治疗效果,可作为一线局部抗真菌药物使用。
Objective To study the therapy reaction to fungal keratitis with cyclosporine A(CsA) and fluconazole.Methods 127 patients(127 eyes) were divided into 2 groups(A or B).The groups A(63 eyes) was treated by fluconazole,the groups B(64 eyes) was treated by fluconazole and cyclosporine A(CsA).Results The groups B was obviously higher than the groups A in vision restoration,obviously effective rate and total effective rate,and obviously lower than the groups A in ineffective rate.There was statistical difference.Conclusion Cyclosporine A(CsA) and fluconazole can significantly enhance trenting results of fungal keratitis,and cyclosporine A(CsA) can be used as the leading locally used drug.
出处
《四川医学》
CAS
2011年第9期1422-1423,共2页
Sichuan Medical Journal
关键词
环孢素A
氟康唑
真菌性角膜炎
cyclosporine a(CsA)
fluconazole
fungal keratitis