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Waldenstrom巨球蛋白血症1例并文献复习

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摘要 1病例介绍 患者男,42岁,汉族。因“脾大、球蛋白增高2年余,面色苍白半年余,头晕、乏力3个月”入院。患者于2007年体检时发现脾肿大、白细胞及球蛋白稍高,2008年体检时除有脾肿大、白细胞及球蛋白升高外,还出现补体降低、IgM增高、血清蛋白电泳出现m带。
机构地区 百色市中医医院
出处 《现代医药卫生》 2011年第19期2956-2957,共2页 Journal of Modern Medicine & Health
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参考文献6

  • 1Ansell SM, Kyle RA, Reeder CB, et al.Diagnosis and management of Waldenstrom macroglobulinemia:Mayo stratification of macroglobu- linemia and risk-adapted therapy (mSMART)guidelines[J].Mayo Clin Proc ,2010,85 (9) :824.
  • 2Kristinsson SY, Koshiol J, M Bjorkholm, et al.Immune-related and inflammatory conditions and risk of lymphoplasmacytic lymphoma or Waldenstrom macroglobulinenaia[J].J Natl Cancer Inst, 2010,102 ( 8 ) :557.
  • 3Royer RH, Koshiol J, Giambarresi TR, et al.Differential characteristics of Waldenstrom macroglobulinemia according to patterns of familial aggregation[J].Blood, 2010,115 (22) : 4464.
  • 4Laszlo D,Andreola G,Rigacci L,et al.Rituximab and subcutaneous 2-chloro-2'-deoxyadenosine combination treatment for patients with Waldenstrom macroglobulinemja:clinical and biologic results of a phase II multicenter study[J].J Clin Oncol,2010,28(13):2233.
  • 5Gertz M A,Abonour R,Heffner LT,et al.Clinical value of minor responses after 4 doses of rituximab in Waldenstrom macroglobulinaemia : a follow-up of the Eastern Cooperative Oncology Group E3A98 trial[J].Br J Haematol, 2009,147 (5) : 677.
  • 6GhobriaI MI, Xie W, Padmanabhan S, et al.Phase II trial of weekly bortezomib in combination with rituximab in untreated patients with Waldenstrom Macroglobulinemia[J].Am J Hematol, 2010,85 (9) : 670.

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