前列地尔冲击治疗椎动脉型颈椎病临床观察

Clinical observation of alprostadil on the vertebroarterial-type cervical spondylopathy

目的观察前列地尔冲击治疗椎动脉型颈椎病的临床效果。方法椎动脉型颈椎病患者120例随机分为治疗组和对照组各60例,治疗组应用前列地尔治疗,对照组应用山莨菪碱(654-2)治疗,观察2组血液流变学变化及临床治疗效果。结果治疗后治疗组血液流变学各项指标均低于治疗前,且低于对照组,差异均有统计学意义(P<0.05)。治疗组有效49例(81.7%),对照组有效32例(53.3%),2组比较差异有统计学意义(P<0.05)。结论前列地尔治疗椎动脉型颈椎病疗效满意,值得临床推广应用。

Objective To observe the effect of alprostadil in treatment of the vertebroarterial-type cervical spondylopathy. Methods 160 paltents with vertebroarterial-type cervical spondylopathy were randomly divided into treatment group and control group （60 in each group）. The treatment group received alprostadil, and the control group recieved 654-2, the hemorheo- logy changes and clinical treatment were observed. Result After treatment, the indicators in treatment group were lower than those before treatment,and lower than those in the control group,and the differences were statistically significant（ P 〈0.05）. 49 cases were effective in treatment group （81.7%） ,and 32 patients （53.3%） were effective in the control group,and the difference was statistically significant （ P 〈 0.05 ）. Conclusion alprostadil in treatment of the vertebroarterial-type cervical spondylopathy is quite effective, and worthy of wide application.