米氮平合并认知治疗对脑卒中后抑郁的疗效对照

Efficacy of Mirtazapine with Cogntive Therapy in Treatment of the Post-stroke Depression

目的探讨米氮平合并认知治疗对脑卒中后抑郁的疗效。方法对72例脑卒中后抑郁患者用米氮平治疗,部分病例合并认知治疗进行临床对照研究;采用汉密尔顿抑郁量表(HAM D)进行疗效评定。结果两组均有效,合并认知治疗组起效快(P<0.05),疗效好。结论米氮平合并认知治疗对治疗脑卒中抑郁疗效较好。

Objective To study the efficacy of Mirtazapine with Cogntive Therapy in treatment of the Post-stroke Depression.Methods A total of 72 post-stroke depression patients were randomly divided into two groups,one group were treated with Mirtazapine,the other were treated with Mirtazapine with Cogntive Therapy,the efficacy was evaluated by HAMD scales.Results Both the groups were effective（P0.01）,but the response was earlier and the efficacy was better in the group teated with Mirtazapine with Cogntive Therapy（P0.05）.Conclusion Mirtazapine with Cogntive Therapy has better efficacy in treatment of the Post-stroke Depression.