红花黄素抗氧化作用在缺血再灌注损伤中的保护机制

Protective mechanism of antioxidation by safflor yellow in ischemia reperfusion injury

红花是传统的活血化瘀类中药。红花黄素是其主要活性成分,红花黄素抗氧化作用、抗缺血再灌注损伤的保护机制主要通过清除氧自由基、对NO的调节、介导NMDA受体表达等途径实现的。文章对缺血再灌注损伤过程中红花黄素抗氧化作用保护机制的最新进展进行综述。

Carthamus tinctorius（CT）,also named safflower,is a TCM widely used to improve blood circulation.Safflor yellow（SY） is the major active component of CT.This paper expounds the protective mechanism of antioxidation by safflor yellow in ischemia reperfusion injury（IRI）.SY plays a key role in IRI protection mainly by eliminating oxygen-derived free radicals,regulating the expression levels of NO and NMDA receptor as well.The article reviews the latest progress made with regard to the protective mechanism of antioxidation by safflor yellow in ischemia reperfusion injury.