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脑源性神经营养因子与抑郁症关系的研究进展 被引量：4

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摘要 神经营养因子（neurotrophin，NT）是一类能促进神经细胞生长、发育和分化的多肽或蛋白质，能调节神经元存活，激活酶的活性，阻止成年神经元损伤后的死亡，具有促进神经元损伤后的修复以及轴突再生，
作者 肖志芳 毕丽丽 邹伟
机构地区 南华大学附属南华医院神经内科
出处 《中国现代医药杂志》 2011年第10期117-119,共3页 Modern Medicine Journal of China
关键词 脑源性神经营养因子 抑郁症 神经元损伤 神经细胞生长 神经元存活 轴突再生 蛋白质 激活酶
分类号 R749.4 [医药卫生—神经病学与精神病学]
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参考文献25

  • 1Rogoz Z, Skuza G, Legutko B. Repeated treatment with mirtazapine induces brain-derived neurotrophic factor gene expression in rats. Physiol Pharmacol,2005,6:661-671.
  • 2Leung DW, Cachianes G, Kuang WJ,et al. Vascular endothelial growth factor is a secreted angiogenic mitogen. Science, 1989,246 (4935):1306-1309.
  • 3Wetmore C, Cao YH, Pettersson RF,et al. Brain-derived neurotrophie factor: subcellular compartmentalization and interneu- ronal transfer as visualized with anti-peptide antibodies. Proc Natl Acad Sci USA,1991,88(21):9843-9847.
  • 4陈兴宝,周学东,季建林,吴文源,王崇顺,史以珏,陈慧云,盛锋,陈卓蕾.上海市抑郁症患者门诊用药与生命质量分析[J].中国药房,2006,17(22):1717-1720. 被引量：9
  • 5Holsboer F, Ising M. Central CRH system in depression and anxiety-evidence from clinical studies with CRH1 receptor antagonists. Eur J Pharmacol,2008,583(2-3):350-357.
  • 6Chaki S, Okubo T, YS. Nonmonoamine-based approach for the treatment of depression and anxiety disorders. Recent Patents on CNS Drug Discovery,2006,1(1):1-27.
  • 7Barinaga M. Developmental biology. Newborn neurons search for meaning. Science,2003,299(5603):32-34.
  • 8Jacobs BL. Adult brain neurogenesis and depression. Brain Behav Immun,2002,16(5):602-609.
  • 9Czeh B, Lucassen PJ. What causes the hippocampal volume decrease in depression? Are neurogenesis, glial changes and apopto- sis implicated? Eur Arch Psychiatry Clin Neurosci,2007,257 (5): 250-260.
  • 10Scharfman H, Goodman J, Macleod A,et al. Increased neurogenesis and the ectopic granule cells after intrahippocampal BDNF infusion in adult rats. Exp Neurol,2005,192(2):348-356.

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共引文献36

同被引文献45

  • 1黎碧娜,曾庆赞,陈楚光.从花生壳中提取天然抗氧化成分的研究[J].现代化工,1995,15(10):31-33. 被引量：21
  • 2Porcelli S,Drago A ,Fabbri C,et al. Phannacogenetics of anti?depressant response. Psychiatry Neurosci. 2011; 36 (2) : 87- 113.
  • 3Zackrisson AL, Lindblom B, Ahlner J. High frequency of oc?currence of CYP2D6 gene duplicationlmultiduplication indi?cating ultra rapid metabolism among suicide cases. Clin Phar?macol Ther. 2010;88:354-359.
  • 4Rudberg I,Mohebi B,Hermann M,et al. Impact of the ultrara- pid CYP2C 19 * 17 allele on serum concentration of escitalo?pram in psychiatric patients. Clin Pharmacol Ther. 2008; 83 : 322-327.
  • 5Uhr M, Tontsch A, Namendorf C, et al. Polymorphisms in the drug transporter gene ABCBl predict antidepressant treatment response in depression. Neuron. 2008; 57 ( 2) :203-209.
  • 6O'Brien FE, Clarke G, Fitzgerald P, et al. Inhibition of P - gly?coprotein Enhances Transport of the Antidepressant Imipra?mine across the Blood-Brain Barrier: Microdialysis Studies in the Conscious Freely Moving Rat. Br J Pharmacol. 2012,on?line.
  • 7Lin KM, Chiu YF, Tsai U, et al. ABCBI gene polymorphisms are associated with the severity of major depressive disorder and its response to escitalopram treatment. Pharmacogenet Genomics. 2011;21(4) :163-170.
  • 8Perroud N , Bondolfi G, Uher R,et al. Clinical and genetic cor?relates of suicidal ideation during antidepressant treatment in a depressed outpatient sample. Pharmacogenomics. 20 II ; 12 (3) :365-377.
  • 9Menu P, Gressier F, Verstuyft C, et al. Antidepressants and ABCB I gene C3435T functional polymorphism: a naturalistic study. Neuropsychobiology, 2010 ; 62 ( 3) : 193- 197.
  • 10Takashi F , Miho 0, Hiroaki H, et al. Association between the functional polymorphism ( C3435T) of the gene encodingP?glycoprotein ( ABCBl ) and major depressive disorder in the Japanese population. Journal of Psychiatric Research, 2012; 46: 555-559.

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中国现代医药杂志
2011年 第10期

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