接种甲型H1N1流感疫苗人群血清抗体阳性率及相关因素分析

Analysis of the antibody positive rate of the population injected influenza A(H1N1) vaccine and the related factors

目的分析甲型H1N1流感疫苗接种效果和影响因素，为流感疫苗接种规划制定提供依据。方法采用分层随机抽样的方法，在2010年1月、4月、8月共抽取1941名甲型H1N1流感疫苗接种者进行问卷调查，并运用血清抗凝实验方法检测抗体水平。结果接种甲型H1N1流感疫苗抗体阳性率为59．5l％，0～岁和60岁及以上人群抗体阳性率较低，6～岁和16～岁人群抗体阳性率较高，抗体水平随时间推移逐渐下降。结论流感疫苗是防止疫情最有效措施之一，在流感高峰期来临前，要加强疫苗接种、补种，特别是60岁及以上的老年人和5岁以下儿童。

Objective To analyze the effect of influenza A（H1N1） vaccination and the related factors, and offer a basis for formulating Influenza vaccination program. Methods 1 941 influenza A（H1N1） vaccinated subjects were chosen by the stratified random sampling in January, April and August, 2010. They were investigated by an uniform questionnaire and their blood samples were tested influenza A（H1 N1 ） antibody by Serum Agglutination Test. Results Positive rate of antibody of influenza A（H1N1） vaccinated subjects was 59.51%, positive rate of antibody among the age group at 0～ years and the age group more than sixty years were lower, that of the age group at 6～ years and the age group at 16～ years were higher. Positive rate of antibody decreased with time. Conclusions Influenza vaccination was one of the best ways to control the spread of influenza, so we need advocate vaccine injection and revaccination, especially in the old men more than sixty years and the children less than 5 years before influenza season.