沙丁胺醇治疗中医热症咳嗽85例分析

Ventolin in the treatment of cough with heat syndrome in 85 patients

目的观察沙丁胺醇在中医热症咳嗽中的治疗效果。方法将本院儿科专家门诊85例西医诊断为上呼吸道炎并经中医辩证为热咳的病人，随机分为治疗组和对照组。两组病人均按西医上呼吸道炎治疗，治疗组在这基础上加用沙丁胺醇，对照组不加沙丁胺醇，均在3天以后复查并记录治疗效果。疗效判定分为显效、好转和无效。全部病人进行变态反应性指标的测定，分别在治疗组和对照组中，将阳性和阴性病例进行对照分析，疗效判定标准同前。结果85例患者分为治疗组43例，对照组42例；结果显示，治疗组显效8例，好转13例，无效22例；对照组显效11例，好转14例，无效17例；两组经统计学处理，差异无显著性（He=1．127，P〉0．05）。而治疗组变态反应性指标阳性者疗效较优于阴性者，两者经统计学处理，差异有显著性（He=5．1，0．05≥P〉0．01）。结论沙丁胺醇在中医的热性咳嗽中无明显的疗效优势，但对具有变态反应性体质的热咳病人，沙丁胺醇则有一定的治疗效果。

Objective To observe the efficacy of ventolin in the treatment of cough with heat syndrome. Methods 85 pediatric patients who had been diagnosed as upper respiratory tract infections by Western medicine and as cough with heat syndrome by Chinese medicine were randomly assigned to receive routine therapy alone （ control group ）, or routine therapy plus ventolin （ study group ）. The efficacy was assessed on day 3 and was classified as cure, improvement, and no failure. The indexes for allergic reactions were detected in all the patients and the patients with positive indexes were compared with those with negative indexes in both groups. Results There was no significant difference in the efficacy between the two groups （ He=1.127, P 〉 0.05 ）. The efficacy differed significantly between the patients with positive indexes and those with negative indexes in the study group （ He = 5.1, 0.05=P 〉 0.01 ）. Conclusions Ventolin has no obvious advantage in the treatment of cough with heat syndrome ; but it has a certain efficacy for patients who have allergic reaction.