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对氧磷酶1与多囊卵巢综合征的相关性研究

The Relationship between PON1 and Polycystic Ovary Syndrome
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摘要 对氧磷酶(PON)是一类能催化水解磷酸酯键的芳香酯酶,能够水解高密度脂蛋白和低密度脂蛋白分子中的氧化型磷脂,具有抗氧化作用。PON活性异常与动脉粥样硬化发生密切相关,PON日益受到重视。随着临床和分子生物学的进展发现,PON的活性与多囊卵巢综合征及其并发症密切相关,但在国内尚未见报道。现就此研究进展作一综述。 Paraoxonase（PON）is a kind of aromatic esterase that can catalyze the hydrolysis of phosphate ester bond in high density lipoprotein and low density lipoprotein with antioxidant activity.Since a close relationship between PON activity and atherosclerosis was found,PON is receiving increasing attention.With the progress of clinical and molecular biology in recent years,foreign scholars have found that PON activity is closely related to polycystic ovary syndrome and its complications.However,no such report has been found in China.Here is to review related progress in this regard.
作者 石溪 周晓梅
机构地区 广东医学院 深圳市福田区妇幼保健院
出处 《医学综述》 2011年第19期2983-2985,共3页 Medical Recapitulate
关键词 对氧磷酶 多囊卵巢综合征 代谢综合征 高密度脂蛋白 低密度脂蛋白 Paraoxonase Polycystic ovary syndrome Metabolic syndrome High density lipoprotein Low density lipoprotein
分类号 R711 [医药卫生—妇产科学]
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参考文献25

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二级参考文献14

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医学综述
2011年 第19期

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