摘要乙型肝炎病毒（Hepatitis B Virus,HBV）感染与慢性乙型肝炎、肝硬化、原发性肝细胞肝癌密切相关。我国是乙型肝炎的高流行区,现有慢性HBV感染者约9 300万人,其中慢性乙型肝炎患者约2 000万例[1]。乙型肝炎病毒感染机体后,大部分被感染者可自发清除病毒,仅5%~10%的被感染者发展为慢性乙型肝炎。不管是病毒因素,还是宿主因素。
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