壳聚糖季铵盐研究进展

Research progress on chitosan quaternary ammonium salt

壳聚糖是应用广泛的天然多糖,资源丰富,壳聚糖化学改性后得到的衍生物改善了壳聚糖的功能,并保留了壳聚糖本身的可生物降解性、生物相容性等优点。其中壳聚糖的季铵盐改性明显提高了其抑菌、抗氧化等活性,并增强了壳聚糖的水溶性,近年来研究较多,介绍了壳聚糖季铵盐的化学改性及应用研究进展,这些化学改性方式均在一定程度上提高了壳聚糖的活性,为壳聚糖的应用奠定了坚实的理论基础。

Chitosan is a natural polysaccharide which is widely used and rich in resource.After chemically modified,the derivatives improved the function of chitosan and retained their biodegradability,biocompatibility,etc.The chitosan quaternary ammonium salt derivatives improved the antifungal,antioxidant activity and the water-soluble properties.There are many researches on these fields in recent years.This paper reviewed the progress of the methods and applications of chitosan quaternary ammonium salt.These methods were all improved the properties of chitosan and the results are theoretically fundamental for further develop and make use of chitosan resources.