老年性股骨粗隆间骨折术后抗骨质疏松治疗的临床研究

Clinical analysis of the treatment with anti-osteoporosis medicine after operation of senile intertrochanteric fracture

目的观察老年性股骨粗隆间骨折术后抗骨质疏松治疗的疗效。方法 82例骨质疏松症并发股骨粗隆间骨折患者,随机分成两组:研究组(A组)和对照组(B组),两组均采用复位、内固定术、功能锻炼治疗,A组同时应用鲑鱼降钙素,碳酸钙D3药物抗骨质疏松治疗,B组未采用抗骨质疏松治疗。结果 A组患者经过治疗后骨密度增加显著(P<0.01)。骨折愈合情况,A组5～7个月愈合率82.93%(34/41),B组5～7个月愈合率26.83%(11/41),两组比较有显著差异(P<0.01)。A组疼痛缓解率56.10%(23/41),B组疼痛缓解率7.32%(3/41),两组比较有显著差异(P<0.01)。结论老年性股骨粗隆间骨折术后抗骨质疏松治疗疗效良好。

Objective To investigate the efficacy of treatment with anti-osteoporosis medicine after operation for senile patients with intertrochanteric fracture. Methods 82 patients suffered intertrochanteric fracture with osteoporosis were randomly divided into two groups： treatment group （group A） and control group （group B）. All patients were performed with reduction, internal fixation and functional exercise. Anti-osteoporosis medicine was applicated in group A, but not in group B. Results Bone mineral density of patients in group A increased significantly than that of patients in group B （P〈0.01）. Percentage of fracture healing 5-7 months after treatment in group A is 82.9% （34/41）, while in group B it is 26.83% （11/41）. There was significant difference between the percentage of fracture healing of Group A and that of Group B （P〈0.01）. Percentage of pain relief in group A is 56.10% （23/41）, while in group B it is 7.32%（3/41）. There was significant difference between the percentage of pain relief of Group A and that of Group B （P〈0.01）. Conclusion Treatment with anti-osteoporosis medicine after operation is effective for senile patients with intertrochanteric fracture.