全血C反应蛋白检测在新生儿感染性疾病诊断中的应用

The application of diagnosis value of the whole blood C-reactive protein in neonatal infections

目的探讨全血C反应蛋白(CRP)检测在新生儿感染性疾病中的诊断价值并与白细胞(WBC)计数进行比较。方法在患儿入院时且在抗生素治疗以前采集外周手指血分别检测全血CRP与WBC水平。结果重症感染组与轻症感染组患儿的全血CRP与WBC水平均显著高于健康对照组(P<0.05);重症感染组患儿全血CRP水平显著高于轻症感染组,差异有统计学意义(P<0.01),两组WBC水平比较差异无统计学意义(P>0.05)。结论与WBC计数相比,全血CRP检测对新生儿感染性疾病具有较好的临床诊断价值。

Objective To explore the diagnosis value of the whole blood C-reactive protein（CRP） in neonatal infections,and compare the result with WBC count.Methods Finger blood CRP and WBC in the peripheral blood of the infected neonate were measured before admission and antibiotic treatment.Results The values of the whole blood CRP and WBC in neonate of the severe infection group and the mild infection group were significantly higher than those of the normal control group children,respectively（P〈0.05）;furthermore,the blood CRP level of the severe infection group was significantly higher than that of the mild infection group（P〈0.01）,the level of WBC was not statistically different between the two groups（P〈0.05）.Conclusion Compared with the WBC count,CRP detection in whole blood of neonatal infections has good clinical application.