2005-2009年云南省与缅甸接壤边境地区维持无脊髓灰质炎工作分析

Keeping polio free status in area bordering Myanmar in Yunnan province,2005-2009

目的评价与缅甸接壤边境地区维持无脊髓灰质炎(脊灰)工作质量,及时发现问题并采取针对性措施,巩固无脊灰成果。方法对云南省与缅甸接壤边境地区急性弛缓性麻痹(acute flaccid paralysis,AFP)监测、脊灰减毒活疫苗(OPV)强化免疫、缅甸入境健康儿童粪便标本脊灰病毒(Poliovirus,PV)检测结果进行分析。结果2005-2009年,与缅甸接壤边境6个州(市)累计报告212例AFP病例,所报病例均排除脊灰,<15岁儿童AFP年均报告发病率为2.03/10万,报告后48小时调查率为98.60%,14天内双粪便采集率为83.97%,合格粪便采集率为81.15%,粪便标本7天内送达率为92.88%,随访及时率为77.64%,AFP病例粪便标本PV分离率和NPEV(非脊灰肠道病毒)分离率分别为2.40%和9.60%。6个州(市)共开展8轮次OPV疫苗强化免疫活动,累计应种儿童3 682 599人,实种3 578 530人,服苗率97.17%。省脊灰实验室检测缅甸入境健康儿童粪便标本856份,PV分离率和NPEV分离率分别为3.74%和13.79%。结论夯实边境州(市)AFP监测各项工作,加强OPV常规免疫和强化免疫,防范脊灰野病毒输入,继续保持无脊灰状态。

Objective To evaluate performance of keeping polio free status in the area bordering Myanmar in Yunnan province and provide evidence for the improvement of the effects to keep polio free status.Methods The data on acute flaccid paralysis（AFP） surveillance,OPV supplementary immunization activities（SIAs） and polio virus detection in stools of healthy Myanmar children who entered into China were analyzed.Results From 2005 to 2009,212 AFP cases were reported in 6 prefectures bordering Myanmar,Poliomyelitis was excluded for all the cases,the annual average AFP reporting rate was 2.03/lakh in children aged15 years.The survey rate of AFP cases within 48 hours after reporting was 98.60%,The collection rate of 2 stool samples within 14 days of onset were 83.97%,the adequate stool samples accounted for 81.15%.The transfer rate of stool samples within 7 days was 92.88% and the timely follow up rate was 77.64%.The isolation rates of polio virus and non-polio enteric virus were 2.40% and 9.60% respectively for the AFP cases and 3.74% and 13.79% for the children from Myanmar respectively,Eight rounds OPV SIAs were conducted during this period and 3.5 million children were immunized Conclusion It is necessary to strengthen the AFP surveillance,routine OPV immunization and OPV SIA in border area to block the introduction of wild polio virus and keep polio free status.