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多囊卵巢综合征的病因及治疗进展 被引量：1

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摘要 多囊卵巢综合征（PCOS）是一种生殖功能障碍与糖代谢异常并存的内分泌紊乱复杂的症候群[1],是生育期妇女常见的内分泌紊乱疾病之一,发病率为5%～10%[2],是以持续无排卵及高雄激素、胰岛素抵抗为主要临床特征。常见临床表现为月经稀发、闭经或月经不调、多毛、肥胖、不孕、痤疮、黑棘皮症、卵巢增大及多囊,以及一系列内分泌改变,其病因、发病机制尚未完全明确,
作者 党裔洁
机构地区 广西北流市陵城镇卫生院
出处 《中国现代药物应用》 2011年第18期120-121,共2页 Chinese Journal of Modern Drug Application
关键词 多囊卵巢综合征 病因 治疗进展
分类号 R711.75 [医药卫生—妇产科学]
  • 相关文献

参考文献12

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  • 2El Mkadem SA,Lautier C,Macari F.Role of allelic variants G1y972Arg of IRS-1 and G1y1057Asp of IRS-2 in moderate-to-severe insulin resistance of women with polycystic ovary syndrome.Diabetes,2006,50(9):2164.
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  • 6刘义,吕立群.罗格列酮治疗多囊卵巢综合征对改善内分泌、代谢及排卵功能的疗效[J].生殖医学杂志,2004,13(3):143-145. 被引量：6
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二级参考文献28

  • 1赵君利,陈子江,赵跃然,赵力新,王来成,李媛,唐蓉,石玉华.性激素结合球蛋白基因启动子(TAAAA)n重复多态及其血清水平与多囊卵巢综合征糖代谢的关联性[J].中华医学遗传学杂志,2005,22(6):644-647. 被引量：9
  • 2李蓉,熊冬梅,许良智.多囊卵巢综合征胰岛素抵抗与基因多态性[J].华西医学,2006,21(2):391-393. 被引量：5
  • 3[1]Michael J, Slowey MD,Concord NC.Polycystic ovary syndrome :New perspective on old problem . Southern Medical Journal , 2001, 94(2):190-196.
  • 4[2]Ajossa S, Guerriero S, Paolelti AM, et al .The antiandrogenic effect of flutamide improves uterine perfusion in women with polycystic ovary syndrome. Fertil Steril, 2002,77(6): 1136-1140.
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  • 6[4]Telli MH , Yildirim M, Noyan V, et al. Serum leptin levels in patients with polycystic ovary syndrome. Fertil Steril, 2002, 77(5): 932-935.
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  • 8[6]Vandermolen DT, Ratts VS, Evans WS, et al .Metformin increases the ovulatory rate and pregnancy rate with clomiphene citrate in patients with polycystic ovary syndrome who are resistant to clomiphene citrate alone. Fertil Steril , 2001,75(3):310-315.
  • 9[7]Ng EH, Wat NM, Ho PC. Effects of metformin on ovulation rate, hormonal and metabolic profiles in women with clomiphene resistant polycystic ovaries: a randomized,double-blinded placebo-controlled trial. Hum Reprod, 2001,16(8): 1625-1631.
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共引文献31

同被引文献36

  • 1陈子江,李媛,周灿权,黄荷凤,刘嘉茵,乔杰,黄国宁,梁晓燕,郁琦.多囊卵巢综合征与辅助生殖的热点问题讨论[J].现代妇产科进展,2004,13(4):241-250. 被引量：58
  • 2黄卫娟,刘嘉茵,李丽娜.环境因素与多囊卵巢综合征发病的相关性分析[J].中华妇产科杂志,2007,42(5):302-304. 被引量：46
  • 3陈小玲,黄水莲.多囊卵巢综合征的研究进展[J].中国误诊学杂志,2007,7(15):3459-3462. 被引量：14
  • 4Goodarzi MO, Dumesic DA, Chazenbalk G, et al. Polycystic ovary syndrome: etiology, pathogenesis and diagnosis [ J ]. Endocrinol, 2011,7(4) :219-231.
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  • 7Kahsar-Miller MD, Nixon C, Boots LR, et al. Prevalence of polycystic ovary syndrome (PCOS) in first-degree relatives of patients with PCOS[J]. Fertil Steril, 2001, 75 (1) : 53-58.
  • 8Jakuhowski L. Genetic aspects of polycystic ovary syndrome (PCOS)[J]. Endokrynol Pol, 2005, 56(3): 285-293.
  • 9Barreca A,Del Monte P,Ponzani P,etal. Intrafotlicular insulin- like growth factor- I] levels in normally ovulating women and in patients with polycystic ovary syndrome (PCOS)[J]. Fertil steril, 1996,65 (4) .. 739-745.
  • 10Vural P, Degirmencioglu S, Saral NY, et al. Tumor necrosis factor ct (-308), interleukin-6 (-174) and interleukin-10 (-1082) gene polymorphisms in polycystic ovary syndrome[J]. Eur J Obstet Gyneeol Reprod Biol, 2010,150 ( 1 ) : 61-65.

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二级引证文献29

中国现代药物应用
2011年 第18期

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