68例急性心肌梗死患者心肌肌钙蛋白T(cTnT)检测结果分析

68 cases of acute myocardial infarction cardiac troponin T(cTnT)test results

目的:探讨心肌肌钙蛋白T(cTnT)检测在急性心肌梗死(AMI)早期诊断中的应用价值。方法:将研究对象分为AMI组(68例)、心绞痛组(41例)、健康对照组(40例)3个组,分别测定3组血清中的肌钙蛋白T(cTnT)、肌酸激酶(cK)和肌酸激酶同工酶(CK—MB)水平并进行比较分析。结果:AMI组68例患者中有64例cTnT检测为阳性,阳性率为94.1%。心绞痛组41例患者中有15例阳性,阳性率为25.0%。健康对照组无1例阳性。AMI组与心绞痛组、健康对照组比较有显著性差异(P<0.05)。在发病后24小时内检测cTnT、CK-MB和CK,68例AMI患者中,cTnT阳性51例,阳性率75.0%;CK-MB阳性30例,阳性率44.1%;CK阳性32例,阳性率47.0%。在41例CHF中,cTnT阳性4例,阳性率9.8%;CK-MB未检出阳性;CK阳性2例,阳性率4.8%,两组比较差异有显著性差异(P<O.05)。结论:肌钙蛋白T灵敏检测法操作简单、快速,在急性心肌梗死(AMI)早期诊断中有较好的应用价值。

Objective： To investigate the cardiac troponin T （cTnT） testing white in acute myocardial infarction （AMI） the value of early diagnosis. Methods： The subjects were divided into KMI group （68 cases）, angina （41 cases） and healthy control group （40 cases） 3 groups, 3 groups were measured in serum troponin T （cTnT）, muscle klnase （eK） and creatine kinase （CK-MB） levels and comparative analysis. Results： AMI group of 68 patients, 64 c, ase~ of cTnT test positive, the positive rate was 94.1%. Angina 15 41 patients were positive in the positive rate was 25.0%. No one healthy control group were positive. Angina group and the AMI group and healthy control group there was significant difference （P 〈 0.05）. Within 24 hours after the onset of de- tect cTnT, CK - MB and CK, 68 cases of AMI patients, eTnT - positive in 51 cases, positive rate of 75.0% ; CK - MB positive for 30 patients, the positive rate of 44.1% ; CK- positive in 32 cases, the positive rate 47.0%. In 41 eases of CHF, cTnT positive in 4 cases, the positive rate of 9.8 % ; CK- MB was not detected positive; CK- positive in 2 cases, positive rate of 4.8%, the difference was significant difference （P 〈 0.05）. Conclusions： Txoponln T sensitive detection method is simple, fast, in acute myocardial infarction （AMI） in the early diagnosis has good application value.