摘要
从茜草根中分得十二个化合物。通过理化性质及光谱分析,确定了八个已知化合物和一个新化合物(Ⅴ),Ⅴ的结构为1,3,6-三羟基-2-甲基蒽醌-3-O-(O-6′-乙酰基)-β-D-吡喃葡萄糖甙(▽)。
Twelve compounds were isolated from the roots of Rubia cordifolia L.. Nine of them were established by chemical and spectroscopic methods te be alizarin (Ⅰ), 1-hydroxy-2-methyl-9, 10-anthraquinone (Ⅱ), 1, 3, 6-trihydroxy-2-methyl,-9, 10-anthra-quinone-3-O-(6'-O-acetyl)-α-L-rhamnosyl(1→2)-β-D-glucoside (Ⅲ), 1, 3, 6-trihydrozy-2-methyl-9, 10-anthraquinone-3-O-α-L-rhamnosyl(1→2)-β-D-giucoside(Ⅳ), 1, 3, 6-trihydrozy-2-methyl-9, 10-anthraquinone-3-O-(6'-O-acetyl)-β-D-glucoside(Ⅴ), 2-carbomethoxy -3-prenyl-1, 4-naphthohydroqumone d_1-β-D-glucoside(Ⅵ), rubimalim(Ⅶ), β-sitosterel (Ⅷ) and daucosterol (Ⅸ), among them, Ⅴ is a nwe compound and Ⅸ was obtained: from this genus for the first time. Ⅲ, Ⅵ and Ⅶ showed certain antibacterial activities.
出处
《药学学报》
CAS
CSCD
北大核心
1990年第11期834-839,共6页
Acta Pharmaceutica Sinica
基金
国家自然科学基金
关键词
茜草
蒽醌
抗菌活性
Rubia cordifblia L.
1, 3, 6-Trihydroxy-2-methyl-9, 10-anthraquinone-3-O-(6'-acetyl)-β-D-glucoside
Anthraquinone