非酒精性脂肪肝相关危险因素分析

Analysis on risk factors of non-alcoholic fatty liver disease

目的:通过流行病学调查,分析NAFLD的相关危险因素,为NAFLD的防治提供理论依据。方法:805人依据体检情况分为NAFLD组和非NAFLD组。所得数据用SPSS15.0软件包进行统计,计量资料行t检验,计数资料行x2检验,患病率随年龄升高趋势行线性趋势检验,多因素分析采用Logistic回归分析。分析年龄、性别、BMI、血压、血脂、血糖等因素与NAFLD的相关性。结果:①男性NAFLD患病率(30.58%)大于女性患病率(19.49%)(P<0.01);女性NAFLD患病率随年龄增长呈升高趋势(P<0.01)。②对NAFLD危险因素指标进行Logistic多因素逐步回归分析,结果显示TG、BMI、FBG、性别(男性)、DBP是NAFLD形成的主要危险因素。结论:NAFLD形成的主要危险因素包括TG、BMI、FBG、DBP、性别(男性)。

Objective：Based on epidemiological investigations,analyzds the relative risk factors of NAFLD,thus providing theoretical reference for the control of NAFLD.Methods：Following the medical check results,805 subjects were divide into non-NAFLD group and NAFLD group.Data obtained were statistically processed with SPSS15.0.Numerical data were analyzed with t test,qualitative data were analyzed with chi-square test,the tendency of sick rate rising with age were analyzed with linear trend test,multi-factors were analyzed with Logistic regression.Analyzed The relations of NAFLD with factors including age,sex,BMI,blood pressure,blood-lipid, blood sugar.Results：①Men’s sick rate of NAFLD（30.58%）is higher than that of women（19.49%）（P〈0.01）;Women’s sick rates show a tendency of increasing with age（P〈0.01）.②Making Logistic multivariate regression analysis for indicators of NAFLD risk factors,the result indicate that TG,BMI,FBG,gender（male）and DBP are major risk factors leading to NAFLD.Conclusion：Major risk factors leading to NAFLD include TG,BMI,FBG,DBP and gender（male）.