摘要
目的：探讨结节性红斑的发因、临床特征以及治疗。方法： 收集39例结节性红斑患者的临床资料，回顾性分析其病因、临床特征、治疗反应及转归。结果：结节性红斑多发生在青年女性中；病因较复杂，其中结核杆菌感染12例，链球菌感染 13例，合并有结缔组织病3例，淋巴瘤1例，病因不明7例。主要表现为双胫前的疼痛性红斑、结节，可伴有关节痛和发热等全身症状。患者对治疗反应较佳，预后良好。结论：结核杆菌以及链球菌等感染是结节性红斑的主要发病原因，要根据不同病因对结节性红斑进行针对性治疗。
Objective： To investigate the causes, clinical features，outcomes of erythema nodosum. Methods： 39 patients with erythema nodosum were analyzed for the etiology, clinical features, treatment outcomes and prognosis by reviewing the clinical date. Results： Erythema nodosum occurs mostly in young women. The etiology was complicated. The common causes were mycobacterium tuberculosis infection, streptococcal infection, connective tissue disease, lymphoma, and so on. The main clinical features was painful erythema and nodule located mostly on anterior shank. Some patients had fever and arthralgia. The patients responsed well to the treatment, and they had a good prognosis. Conclusion： Mycobacterium tuberculosis, and streptococcal infection were the main causes of erythema nodosum. Trement should based on the different causes of erythema nodosum.
关键词
结节性红斑
治疗
发病原因
临床特征
erythema nodosum
treatment
pathogenesis
clinical features
