浦东新区20～80岁居民代谢综合征的流行特征

Epidemiological features of metabolic syndrome in residents aged 20-80 years in Pudong New District of Shanghai

目的了解上海市浦东新区居民代谢综合征（MS）的患病率及其分布特征。方法2008年4月至7月期间，采用多阶段随机抽样方法，从上海市浦东新区抽取20—80岁的社区居民5584人，进行横断面调查，根据美国国家胆固醇教育计划成人治疗组修正第3次报告（NCEP-ATPⅢ）、国际糖尿病联盟（IDF）、中华医学会糖尿病学分会（CDS）诊断标准计算MS各组分患病率，并比较3种标准应用的差异。结果根据CDS的MS诊断标准，上海市浦东新区成年居民MS患病粗率为18．2％，世界人口标化率为13．1％（男性19．1％，标化后15．6％；女性17．4％，标化后13．2％）；根据NCEP—ATPⅢ的MS修订标准MS患病粗率为31．8％，世界人口标化率为24．4％（男性28．4％，标化后22．7％；女性35．1％，标化后25．0％）；根据IDF的MS诊断标准MS患病粗率为21．7％，世界人口标化率为17．0％（男性15．9％，标化后13．8％；女性26．7％，标化后19．2％）。无论何种诊断标准，MS的患病率均随年龄增加而升高；且男性年龄别患病率在低年龄时高于女性，随年龄增长逐渐低于女性。按特定标准，MS患病率分别在地区、文化程度、婚姻状况、吸烟、工作强度和休闲体力活动方面存在差异。结论浦东新区成人中有相当比例个体患有MS，并存在年轻化趋势，提示MS已成为影响居民生命和健康的重大公共卫生问题，亟需制定MS为先导的社区综合防治的卫生策略。

Objective To investigate the prevalence and risk factors of metabolic syndrome （MS） in residents in Pudong New District of Shanghai. Methods A total of 5 584 residents aged 20-80 years were randomly selected from Pudong New District of Shanghai through multistage sampling and interviewed from April to July of 2008. Metabolic syndrome was defined according to three diagnostic criteria for MS, issued by the modified National Cholesterol Education Program Adult Treatment Panel Ⅲ criteria （ NCEP -ATPⅢ ）, International Diabetes Federation （IDF）, and Chinese Diabetes Society （CDS）. Results The crude prevalences of MS in the adult population in Pudong New District were 18.2% and 13. 1% standardized （male 19. 1%, female 17.4%, the age-standardized 15.6% and 13.2% ） with CDS criterion, 31.8 % and 24.4% standardized （ male 28.4% , female 35.1%, the agestandardized 22.7% and 25.0% ） with NCEP-ATP Ⅲ criterion, and 21. 7% and 17. 0% standardized （ male 15.9% ,female 26.7% ,the age-standardized 13.8% and 19.2% ） with IDF criterion. The age-specific prevalence of MS increased according to three diagnostic criteria, and the age-adjusted prevalence was higher in males than females in junior age groups and higher in females than males in senior ones. Significant differences were present among region, education, marriage status, smoking, work intensity, recreation, and physical activity according to some diagnostic criteria. Conclusions Substantial proportions of aduhs in Pudong New District of Shanghai suffer from metabolic syndrome, and there exists a tendency for young people involved. MS has become a noteworthy public health problem. It suggests that community-integrated control strategy of MS should be made a priority.