儿童环状肉芽肿7例临床分析

Clinical Analysis of 7 Patients With Granuloma Annulare in Children

目的提高临床医生对儿童环状肉芽肿的认识,探讨其诊断依据和最佳治疗方法。方法对收集的7例环状肉芽肿患儿的临床资料进行回顾分析。结果 7例患儿中,女5例,男2例。临床表现为淡黄色或红色环状丘疹或皮下斑块,多发于四肢。皮损组织病理示:真皮或皮下组织中有栅状排列的组织细胞团,其中心可见胶原变性。结论环状肉芽肿属良性自限性疾病,可依据组织病理进行诊断。

Objective To get inside view of granuloma annulare in childhood and to explore the diagnostic evidence and therapeutic methods. Methods A retrospective analysis of the clinical data from 7 patients with this disorder in children was performed. Results We report the typical lesion of 7 cases,5 girls and 2 boys were small, skin-colored or red papules with an annular distribution or subcutaneous masses. Lesions tend to occur on the extremities. The histopathology showed that granulomas with palisading histiocytes around necrobiotic collagen center in the dermis or subcutaneous tissue. Conclusion GA is a self-limited, benign inflammatory skin lesion. The definite diagnosis is based upon biopsy study.