丹红注射液对不稳定型心绞痛患者血流动力学和高敏C反应蛋白的影响

Affection of Hemorrheology and Hyper-sensitive C-RP of Danhong Injection on Unstable Angina

目的探讨丹红注射液对不稳定型心绞痛患者血流动力学和高敏C反应蛋白(hs-CRP)的影响及临床疗效。方法将64例不稳定型心绞痛患者随机分为两组,对照组常规给予硝酸酯类药物、β-受体阻滞剂、抗凝、抗血小板聚集药物、血管紧张素转换酶抑制剂、他汀类药物及控制血压和/或血糖等治疗;治疗组在常规治疗基础上,加用丹红注射液30 mL加入生理盐水250 mL,静脉滴注,1次/d。两组疗程均为14 d。观察两组在治疗前后血流动力学变化和hs-CRP水平及临床疗效。结果治疗组临床疗效的总有效率为87.5%,高于对照组的65.6%(P<0.05);治疗后,治疗组血流动力学改善明显和降低hs-CRP水平有统计学意义(P<0.05)。结论丹红注射液可明显改善不稳定型心绞痛患者血流动力学指标和降低hs-CRP水平,是治疗不稳定型心绞痛安全有效的药物。

Objective To discuss the affection of hemorrheology and hs-CRP of Danhong injection on unstable angina.Methods 64 cases of such patient were divided into two groups.The control group was treated with routine method of nitrate,β-RB,anticoagulator,ACI,statins and so on.The test group was treated with Danhong injection based on routine therapy.Both group were treated twice weeks as a course.The hemorrheology and hs-CRP were observed in two groups.Results The total effective rate was 87.5% in test group and 65.6% in control group with P0.05.The hemorrheology improved and hs-CRP decreased had significant difference in two groups.Conclusion Danhong injection might improve the hemorrheology and decrease hs-CRP for such patient with effective and safe reaction.