中西医结合治疗原发性胆汁性肝硬化30例

Clinical Reports of Patients with Primary Biliary Cirrhosis Treated by Integrated Traditional and Western Medicine

目的通过比较中西医结合治疗及单纯西医治疗原发性胆汁性肝硬化的临床疗效,探讨PBC的中西医结合治疗策略。方法回顾性分析62例诊断为PBC的住院患者,根据是否应用中药,分为中西医结合治疗组(治疗组)及西医对照组(对照组),对照组给予口服熊去氧胆酸治疗及常规内科保肝、对症支持治疗,治疗组在给予对照组相同治疗基础上应用辨证中药。结果与对照组相比,治疗组TBil、DBil、ALP、ALT指标改善明显,P<0.05。临床有效率治疗组为80.0%,对照组为56.3%,治疗组疗效明显优于对照组,P<0.05。结论中西医结合治疗原发性胆汁性肝硬化可明显提高临床疗效。

Objective Searching the treatment regimen of primary biliary cirrhosis by traditional Chinese medicine combined with western medicine through comparing this treatment method and western medicine only.Methods Retrospective analysis of 62 inpatients diagnosed as PBC,According whether Chinese herbs are used,the patients are divided into integrate treatment group of traditional Chinese medicine and western medicine,called as treatment group,and western medicine treatment group,called as control group.The control group are given ursodesoxycholic acid orally and routine protecting liver and supportive treatment,treatment group are given Chinese herbs additionally based on western medicine.Result Combined with the control group,Index of TBIL,DBIL,ALP,ALT of treatment group are improved significantly,P0.05.The clinical efficacy of treatment group is 80.0%,which is better than the control group＇s 56.3%,P0.05.Conclusion It can increase clinical efficacy of PBC through integrate treatment of traditional Chinese medicine and western medicine.