青年脑梗死患者颈动脉彩色多普勒超声分析

Analysis on the Ultrasonic Characteristics of Young Patients with Cerebral Infarction

目的评价青年人颈动脉彩色多普勒超声检查的临床意义,并探讨青年人脑梗死与颈动脉粥样硬化的关系。方法 2008年2月-2011年3月,对256例青年脑梗死患者进行颈动脉彩色多普勒超声检测,选择性别和年龄匹配的健康青年143例作对照组,比较两组人群颈动脉彩色多普勒超声特点的差异。结果脑梗死组颈动脉粥样硬化斑以中等、强回声斑块为主,斑块积分、血管壁内-中膜厚度(ITM值)及斑块检出率(34.77%,89例)均明显高于对照组(P<0.01);脑梗死组颈动脉硬化狭窄率及血栓发生率明显高于对照组(P<0.05,<0.01)。结论青年脑梗死患者颈动脉粥样硬化及血栓形成发生率均高,提示青年脑梗死患者的发病主要原因与动脉粥样硬化有关。IMT值的增加、斑块的检出率及形态学特征等是颈动脉病变与脑梗死发生的有意义的检测指标,在青年人脑梗死的防治中是有参考意义较大的超声学指标。

Objective To assess the clinical significance of color Doppler ultrasonography in examining carotid arteries of young patients, and explore the relationship between cerebral infarction and carotid arteriosclerosis in young patients. Methods A total of 256 patients with cerebral infarction and 143 people without cerebral infarction diagnosed between February 2008 and March 2011 were assessed by color doppler ultrasonography. The ultrasonic characteristics of the two groups were compared and analyzed. Results Plaques incidence in cerebral infarction group was 81.43% which was higher than that in the control group. The most common sites of plaque formation were common carotid artery （CCA） bifurcate and the initial segment of internal carotid artery （ICA） in young people with cerebral infarction. In the cerebral infarction group, the rate of middle-echoic plaques was higher than that in the control group （P〈0.05）. The rate of low-grade carotid stenosis was higher in the cerebral infarction group than that in the control group （P〈0. 05）. Conclusions Cerebral infarction occurrence in young people is closely correlated to carotid artery atherosclerosis. Ultrasonography can provide objective evidences for preventing and treating cerebral infarction.