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VEGF-C在乳腺癌中的表达及其与临床病理因素的关系

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摘要 目的:探讨血管内皮生长因子-C(VEGF-C)与乳腺癌临床病理因素的关系。方法:运用原位杂交的方法检测89例乳腺癌石蜡标本中的VEGF-C mRNA的表达。结果:VEGF-C阳性率为55.1%(49/89),其中淋巴结有转移组(HE染色阳性)为79.2%(19/24),明显高于淋巴结无转移组(42.1%,16/38),二者比较有显著差异(P<0.05),但与月经、肿瘤大小、病理类型、临床分期、ER、nm23、c-erbB2无关(P>0.05)。结论:VEGF-C的表达与乳腺癌的淋巴结转移相关,但与病人的月经情况、肿瘤大小、病理类型、临床分期、ER、nm23、c-erbB2无关。
出处 《陕西医学杂志》 CAS 2011年第10期1314-1316,共3页 Shaanxi Medical Journal
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