血清C-反应蛋白在小儿肺炎中的临床应用

The clinical application of the serum CRP in infantile pneumonia

目的观察血清C-反应蛋白(CRP)水平在小儿细菌性肺炎、支原体肺炎和病毒性肺炎中的变化。方法选择明确诊断为肺炎的120例小儿患者,根据病因分为细菌性肺炎组、支原体肺炎组和病毒性肺炎组(分别简称细菌组、支原体组和病毒组),每组40例,进行血清C-反应蛋白的测定,观察其浓度的变化,并进行统计学分析。结果入院时细菌组与支原体组、病毒组血清CRP比较,差异有统计学意义(P<0.01),病毒组与支原体组比较差异无统计学意义(P>0.05);治疗2周后细菌组CRP较入院时明显下降,差异具有统计学意义(P<0.01)。结论血清CRP在小儿肺炎的鉴别诊断中具有重要的临床意义。

Objective To investigate changes of the serum CRP levels in infantile bacterial pneumonia,mycoplasmal pneumonia and virus pneumonia.Methods 120 children with pneumonia were divided into three groups： the bacterial group,the mycoplasmal group and the virus group.Their serum CRP levels were measured and the changes of their concentration were observed and analyzed statistically.Results At the beginning of being hospitalized,compared with the levels of the mycoplasmal group and the virus group,the serum CRP levels of the bacterial group were significantly different（P0.01）,while there was no significant difference between the mycoplasmal group and the virus group（P0.05）.After 2 weeks＇ treatment,compared with the former,the serum CRP levels of the bacterial group decreased significantly,which was statistically significant difference（P0.01）. Conclusion The serum CRP level has clinical significance in the differential diagnosis of infantile pneumonia.