输卵管妊娠腹腔镜保守手术治疗和化学药物保守治疗疗效对比观察

Comparison on the effect of laparoscopic oviduct sparing operation and chemotherapy in treatment of tubal pregnancy

目的对比观察腹腔镜保守手术和化学药物对输卵管妊娠治疗效果。方法回顾性分析该院2007年6月～2009年2月收治的94例输卵管妊娠患者,按照治疗方法不同分为观察组(n=48)和对照组(n=46),观察组予腹腔镜保守手术,对照组予甲氨蝶呤-米非司酮化疗,对两组出院时情况及随访结果进行比较分析。结果观察组有效率97.92%,对照组为93.48%。观察组住院时间及出院时血HCG水平明显低于对照组,差异有显著性(P<0.05)。观察组患侧输卵管通畅率和再次宫内孕的发生率明显高于对照组,差异有显著性(P<0.05)。两组同侧异位妊娠的发生率比较,差异无显著性(P>0.05)。结论与化学药物保守治疗相比,尽管腹腔镜保守手术预防再次同侧异位妊娠的效果不明显,但仍具有明显优势,是输卵管妊娠保守治疗中一种安全、可靠的方法。

[Objective] To compare the clinical outcomes between laparoscopic conservative surgery and chemotherapy in treatment of tubal pregnancy.[Methods] A total of 94 patients with tubal pregnancy were divided into two groups,observation group（n =48） and control group（n =46）.The observation group was treated with laparoscopic oviduct-sparing operation and control group was treated with chemotherapy.The clinical information was compared between the two groups.[Results] The time of hospitalization and level of HCG on the discharge day of the observation group were significant less than those of the control group,while the potency rate of common oviduct and conception rate of the observation group were significant higher than those of the control group.But there was no significant difference of incidence of the same side reectopic pregnancy between the two groups.[Conclusions] Laparoscopic oviduct-sparing operation has the advantages in treatment of ectopic pregnancy.It is a safe and effective method,which is worth of applying in practice.