妇炎消胶囊中非法成分土大黄苷的检测

Determination of Rhaponiticin Illegally Added in Fuyanxiao Capsules

目的建立妇炎消胶囊中非法成分土大黄苷的定性检测方法。方法采用薄层色谱法、高效液相色谱法对怀疑有非法成分土大黄苷的妇炎消胶囊进行分离分析,并采用高效液相色谱-二极管阵列检测法对其进行定性鉴别。结果在妇炎消胶囊中检测有非法成分土大黄苷。结论该方法专属性强、灵敏度高、操作简便,可作为检测非法成分土大黄苷的有效方法。

OBJECTIVE To establish a method for determination of rhaponiticin illegally added in Fuyanxiao capsules.METHODS TLC and HPLC were employed to isolate and analyze the extract from Fuyanxiao capsules suspected of illegal composition of rhaponiticin,and rhaponiticin was identified by HPLC-DAD.RESULTS Fuyanxiao capsules were detected to contain illegal composition of rhaponiticin.CONCLUSION The established method is specific,sensitive and convenient.It can be used efficiently for control and surveillance of illegal composition of rhaponiticin in Fuyanxiao capsules.