期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

视黄醇结合蛋白4与胰岛素抵抗的研究进展

原文传递
导出
摘要 长期以来，脂肪组织一直被认为仅是机体供能的器官。但随着研究的不断深入，开始认识到脂肪组织还是一种内分泌器官，能分泌瘦素、脂联素、脂肪源性肿瘤坏死因子一a（TNF-a ）、白细胞介素-6（IL-6）等多种脂肪因子来调节胰岛素在各组织器官的作用，参与胰岛素抵抗（insulinresistance，IR）的发生与发展。
作者 未友能 李启富
机构地区 重钢总医院老年内分泌科 重庆医科大学附属第一医院内分泌科
出处 《中华内分泌外科杂志》 CAS 2011年第5期345-347,共3页 Chinese Journal of Endocrine Surgery
基金 国家自然科学基金（81070668）
关键词 胰岛素抵抗 视黄醇结合蛋白4 内分泌器官 脂肪组织 肿瘤坏死因子 白细胞介素 组织器官 脂肪因子
分类号 R587 [医药卫生—内分泌]
  • 相关文献

参考文献22

  • 1Tamori Y, Sakaue H, Kasuga M. RBP4, an unexpected adipokine [J].Nat Med,2006 ; 12( 1 ) :30-31.
  • 2Yang Q, Graham TE, Mody N, et al. Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes[J]. Nature, 2005, 436(7049):356-362.
  • 3Graham TE, Yang Q, Bltiher M, et al. Retinol-binding protein 4 and insulin resistance in lean, obese, and diabetic sulgjects[ J ]. N Engl J Med. 2006.354(24) :2552-2563.
  • 4王清生,张明军.8周游泳运动对糖尿病大鼠RBP4mRNA表达的影响[J].山东体育学院学报,2008,24(8):44-46. 被引量：7
  • 5未友能,青华,段炼,梅玫,程庆丰,李启富.TNF-α抑制成熟3T3-L1脂肪细胞分泌RBP4[J].重庆医科大学学报,2008,33(5):575-577. 被引量：3
  • 6Sell H, Eckel J. Regulation of retinol binding protein 4 production in primary human adipoeytes by adipnnectin, troglitazone and TNF- alpha [ J ]. Diabetologia, 2007, 50 ( 10 ) : 2221-2223.
  • 7Vitkova M, Klimcakova E, Kovacikova M, et al. Plasma levels and adipose tissue messenger ribonueleic acid expression of retinol-binding protein 4 are reduced during calorie restriction in obese subjects but are not related to diet-induced changes in insulin sensitivity [ J]. J Clin Endocrinol Metab, 2007,92 (6) :2330-2335.
  • 8Takebayashi K, Suetsugu M, Aso Y, et al. Retinol-binding protein-4 level and clinical features of type 2 diabetes patients [ J ]. J Clin Endocrinol Metab,2007,92(7) :2712-2719.
  • 9Lee DC, Lee JW, Im JA. Association of serum retinol binding protein 4 and insulin resistance in apparently healthy adolescents[ J]. Metabolism,2007,56 ( 3 ) : 327-331.
  • 10Stefan N, Hennige AM, StaigerH, et al. High circulating retinolinding protein 4 is associated with elevated liver fat but not with total, subcutaneous, viscera, or intramyocellular fat in humans [ J ]. Diabetes Care,2007,30 (5) : 1173-1178.

二级参考文献31

  • 1Cho YM, Youn BS, Lee H, et al. Plasma Retinol- Binding Protein-4 Concentrations Are Elevated in Human Subjects With Impaired Glucose Tolerance and Type 2 Diabetes [J]. Diabetes Care, 2006,29( 11 ) : 2457-2461.
  • 2Yang Q, Graham TE, Mody N, et al. Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes [ J ]. Nature, 2005,436 ( 7049 ) : 356-362.
  • 3Graham TE, Yang Q, Bluher M,et al. Retinol-binding protein 4 and insulin resistance in lean, obese, and diabetic subjects [ J]. N Engl J Med , 2006, 354 ( 24 ) :2552-2563.
  • 4Janke J, Engeli S, Boschmann M, et al. Retinolbinding protein 4 in human obesity [ J ]. Diabetes, 2006,55 (10) :2805-2810.
  • 5Gomez-Ambrosi J,Rodrguez A,Catalan V, et al. Serum retinol-binding protein 4 is not increased in obesity or obesity-associated type 2 diabetes mellitus, but is reduced after relevant reductions in body fat following gastric bypass [ J ]. Clin Endoerinol (Oxf) , 2008,69 (2) :208-215.
  • 6Stefan N, Hennige AM, Staiger H, et al. High circulating retinol-binding protein 4 is associated with elevated liver fat, but not with total-, subcutaneous-, visceral-, or intramyocellular fat in humans [ J ]. Diabetes Care,2007,30(8) : 1173-1176.
  • 7Chan TF,Chen HS,Chen YC, et al. Increased serum retinol-binding protein 4 concentrations in women with gestational diabetes mellitus [ J ]. Reprod Sei ,2007, 14(2) :169-174.
  • 8Lain KY, Daftary AR, Ness RB, et al. First trimester adipocytokine concentrations and risk of developing gestational diabetes later in pregnancy [ J ]. Clin Endocrinol (Oxf) , 2008,69(3):407-411.
  • 9Blaner WS.Retinol-binding protein:the serum transport protein for vitamin A[J].Endocrine Rev,1989 ; 10(3):308-316.
  • 10Yang Q,Timothy E,Mody N,et al.Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes[J].Nature,2005 ; 436(7049):356-362.

共引文献13

中华内分泌外科杂志
2011年 第5期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部