雌激素结合中药汤剂预防宫腔镜分离后宫腔粘连的疗效分析

The efficacy analysis of estrogen combined with traditional Chinese medicine decoction for prevention intrauterine adhesions after hysteroscopy surgery

目的:探讨雌激素结合中药汤剂预防宫腔镜分离后宫腔粘连的疗效与安全性。方法:将40例宫腔镜电切术后患者随机分为治疗组和对照组,每组20例。对照组术后口服戊酸雌二醇预防宫腔粘连,而治疗组在对照组基础上加用中药汤剂预防宫腔粘连。结果:治疗组与对照组的宫腔粘连发生率分别为10%(2/20)和30%(6/20),治疗组与对照组比较,宫腔粘连的发生率明显减少(P<0.05),并且治疗组术后宫腔粘连的程度和范围均低于对照组;两组不良反应情况,治疗组发生不良反应1例,对照组无不良反应发生,两组比较,差异无统计学意义(P>0.05)。结论:雌激素结合中药汤剂预防宫腔镜分离后宫腔粘连的疗效好,预防范围广,安全性强,值得推广应用。

Objective： To investigate the efficacy and safety of estrogen combined with traditional Chinese medicine decoction for prevention of intrauterine adhesions after hysteroscopy surgery. Methods： 40 cases of patients after hysteroscopy surgery were equally randomly divided Jr/to treatment group and control group. Only Estradiol Valerate was administrated in the control group after surgery for preventing intrauterine adhesion, while estrogen combined with traditional Chinese medicine decoction were administrated in the treatment group. Results： The incidence of intrauterine adhesion in treatment group and control group were accounted for 10% （2/20） and 30% （6/20） respectively, compared with control group, the incidence of intrauterine adhesion in treatment group was significantly reduced （P〈0.05）, while the extent and scope of intrauterine adhesions in treatment group were lower than that of control group. 1 case of adverse reaction occurred in treatment group, and there was no adverse reaction in control group, the adverse reaction of the two groups had no significant difference （P〉0.05）. Conclusion： Estrogen combined with traditional Chinese medicine decoction for prevention of in- trauterine adhesions after hysteroscopy surgery is effective and has a wide range of strong security, which is worthy of clinical application.